广西医科大学学报2024，Vol.41Issue(4)：621-628,8.DOI:10.16190/j.cnki.45-1211/r.2024.04.020
非肿瘤疾病中SERPINA3/Serpina3c介导的细胞信号轴的研究进展
The research progress of SERPINA3/Serpina3c mediated cell signaling axis in non-tumor dis-eases
摘要
Abstract
SERPINA3/Serpina3c is a serine(or cysteine)peptidase inhibitor that inhibits cathepsin G and exerts anti-inflammatory effects.At present,most of the understanding of the functions of SERPINA3/Serpina3c comes from studies in the context of carcinogenesis.SERPINA3/Serpina3c is involved in various cellular biological pro-cesses such as gene expression,cell cycle progression,apoptosis,signal transduction,and carcinogenesis.In re-cent years,the study on SERPINA3/Serpina3c in non-tumor diseases is increasing.This article systematically ana-lyzes the research hotspots and trends of SERPINA3/Serpina3c,reviews its regulatory mechanisms on the cell sig-naling axis in non-tumor diseases,and provides some ideas for the molecular mechanism research of SERPINA3/Serpina3c in non-tumor diseases.关键词
SERPINA3/Serpina3c/信号通路/CiteSpace/文献计量分析Key words
SERPINA3/Serpina3c/signal pathway/CiteSpace/bibliometric analysis分类
医药卫生引用本文复制引用
覃梦岚,朱素梅,黎芳,梁健钦,丘琴..非肿瘤疾病中SERPINA3/Serpina3c介导的细胞信号轴的研究进展[J].广西医科大学学报,2024,41(4):621-628,8.基金项目
国家自然科学基金资助项目(No.81960872) （No.81960872）
广西自然科学基金资助项目(No.2020GXNSFAA238035) （No.2020GXNSFAA238035）
