摘要
Abstract
Objective To investigate the effect of bioimpedance analysis(BIA)-guided ultrafiltration on remaining renal function(RRF)in hemodialysis patients compared with conventional clinical methods.Methods PubMed,Cochrane Library,Embase,Web of Science,CNKI,Wanfang,VIP,and CBM were searched for randomized controlled trials(RCTs)about the effects of BIA-guided ultrafiltration on RRF in hemodialysis patients compared with conventional clinical methods from the inception to December 31,2022.Meta-analysis was performed by RevMan 5.4.Results A total of 6 RCTs with 406 participants were included.The results of meta-analysis showed that the RRF[P＜0.05,MD=1.15,95％CI(1.00,1.31)]and 24 h urine output[P＜0.05,MD=253.56,95％CI(229.17,277.96)]of the BIA guidance group were higher than those of the control group,and the ultrafiltration volume[P＜0.05,MD=-0.45,95％CI(-0.65,-0.26)]and diastolic blood pressure[P＜0.05,MD=-5.52,95％CI(-7.58,-3.47)]were lower than those of the control group,but there were no statistically significant differences in the systolic blood pressure[P＞0.05,MD=-0.25,95％CI(-7.70,7.21)],body weight[P＞0.05,MD=-0.01,95％CI(-3.38,3.37)],or albumin[P＞0.05,MD=0.41,95％CI(-1.61,2.43)]between the two groups.Conclusion Based on the existed data,compared with conventional clinical methods,BIA-guided ultrafiltration can protect the RRF in hemodialysis patients.关键词
血液透析/残余肾功能/生物电阻抗分析/meta分析Key words
Hemodialysis/Residual renal function/Bioimpedance analysis/Meta-analysis
