海南医学院学报2024，Vol.30Issue(8)：634-640,7.DOI:10.13210/j.cnki.jhmu.20230828.002
功能性消化不良病证结合动物模型研究进展
Research progress on animal models of functional dyspepsia combined with syndrome differentiation
摘要
Abstract
Functional dyspepsia(FD)is a common digestive system disease with unclear pathogenesis and no organic lesions.The treatment plan and strategy urgently need to be further explored.Establishing a mature and complete animal model combining FD disease and syndrome can help further explore the pathogenesis of the disease and evaluate the therapeutic effect of traditional Chinese medicine formulas.This study aims to analyze the commonly used animal modeling methods and evaluation indicators for spleen deficiency syndrome,liver depression syndrome,and liver depression spleen deficiency syndrome in FD.The combination of improper diet or excessive fatigue during the modeling process is more conducive to the stability of the model,which is related to modern lifestyle habits.Spleen deficiency is the foundation of FD.Designing mature and complete animal modeling methods for spleen deficiency in FD may provide new treatment directions and better treatment strategies for treating FD.The existing evalua-tion indicators for the combination of FD disease and syndrome models generally have strong subjectivity and insufficient objective evidence.How to improve the evaluation system for the combination of FD disease and syndrome animal models is a direction that needs to be worked on in the future.关键词
功能性消化不良/动物模型研究/病证结合/中医证型/研究进展Key words
Functional dyspepsia/Animal model research/Combination of disease and syndrome/TCM syndrome/Re-search progress分类
医药卫生引用本文复制引用
邓娴,谭瑾轩,陈映西,潘娜,刘付杰义,黄晓燕..功能性消化不良病证结合动物模型研究进展[J].海南医学院学报,2024,30(8):634-640,7.基金项目
This study was supported by Guangxi Innovation-Driven Development Project(Guike AA17202031) 广西创新驱动发展专项(桂科AA17202031) （Guike AA17202031）
