流动聚焦型液滴微流控技术研究进展OA北大核心CSTPCD

Functional microspheres are frequently used in controlled drug release,biomedicine,pollutant adsorption and catalysts due to their high specific surface area,stable characteristics and variable forms.Spray drying,suspension polymerization,ionic cross-linking,emulsion evaporation and droplet microfluidization are typical techniques used to prepare microspheres.Microfluidization has advantages of low chemical usage,high safety and monodispersity,while flow-focused microfluidics can efficiently prevent droplet shearing with wall,and the droplet size can be easily controlled.This review discusses research development of experimental and numerical simulation of functional microsphere preparation and its integrated amplification processes,which can provide a guidance for the preparation of innovative functional microspheres and industrial mass production.