摘要
Abstract
Objective To compare the efficacy and immune function of endoscopic retrograde appendecto-my(ERAT)and laparoscopic appendectomy(LA)in the treatment of patients with acute appendicitis(AA)abscess.Methods The clinical data of 80 patients with AA abscess in the hospital from May 2021 to May 2023 were retrospectively collected and divided into group A and group B according to different surgical proto-cols,40 cases in each group.The group A was treated with ERAT,while the group B was treated with LA.The surgical and postoperative recovery indicators(including the time of body temperature renormalization,the time of getting out of bed,the time of operation,the time of gastrointestinal function recovery and the intr-aoperative blood loss),the visual analogue scale(VAS)scores,gastrointestinal hormones[gastrin(GAS),va-soactive intestinal peptide(VIP),motilin(MTL)],immune function(CD3+,CD4+,CD4+/CD8+)levels and the incidence of complications between the two groups were compared.Results Compared with the group B,the time of body temperature renormalization,the time of getting out of bed,the time of operation,and the time of gastrointestinal function recovery in group A were shorter,and the intraoperative blood loss was less,with statistically significant differences(P<0.05).The VAS score of the group A was lower than that of the group B at 1 d after surgery(P<0.05).Serum GAS and MTL levels in the group A were higher than those in the group B at 1 d after surgery,and serum VIP level was lower than that in the group B,with statistically sig-nificant differences(P<0.05).The levels of CD3+,CD4+,CD4+/CD8+ in the group A were higher than those in the group B(P<0.05).The total complication rate in the group A was 2.50%(1/40),which was significantly lower than that in the group B[20.00%(8/40)],with statistically significant difference(P<0.05).Conclusion Compared with LA,ERAT has more prominent advantages in the treatment of AA ab-scess,which can not only further optimize operation and postoperative recovery indicators,reduce complica-tions and alleviate postoperative pain,but also have less influence on gastrointestinal and immune functions.关键词
急性阑尾炎脓肿/内镜下逆行阑尾炎治疗术/腹腔镜阑尾切除术/胃肠激素/免疫功能/并发症Key words
acute appendicitis abscess/endoscopic retrograde appendectomy/laparoscopic appendecto-my/gastrointestinal hormone/immune function/complication分类
医药卫生
