摘要
Abstract
Objective To evaluate the clinical value of CT morphological features in the diagnosis of viscer-al pleural invasion in lung adenocarcinoma.Methods Sixty-eight patients with lung adenocarcinoma in Nan-tong Haimen District People's Hospital from September 2018 to September 2021 were selected and classified into invasion group(n=27)and non-invasion group(n=41)according to pathological findings of visceral pleural invasion in lung adenocarcinoma.The CT morphological features of patients in the two groups were compared,and multivariate Logistic regression analysis was adopted to analyze the risk factors for pleural in-vasion in lung adenocarcinoma;the receiver operating characteristic(ROC)curve was plotted to evaluate the predictive efficacy of the risk scoring model for pleural invasion.Results The proportions of patients with margin burr sign,cavity sign in tumor and pleural indentation sign in the invasion group were significantly higher than those in the non-invasion group(P<0.05).The proportions of patients with maximum diameter of solid portion of tumor>10 mm,solid proportion of tumor>50%and the presence of lesions abutting the pleura in the invasion group were significantly higher than those in the non-invasion group(P<0.05).Multi-variate Logistic regression analysis showed that margin burr sign,cavity sign in tumor,pleural indentation,maximum diameter of solid portion of tumor>10 mm,solid proportion of tumor>50%and the presence of lesions abutting the pleura were independent risk factors for visceral pleura invasion in lung adenocarcinoma(P<0.05).The AUC,sensitivity and specificity of the risk score model created based on theβvalues of the independent risk factors for visceral pleural invasion in patients with lung adenocarcinoma in predicting viscer-al pleural invasion were 0.916,96.3%and 75.6%,respectively.Conclusion The model created based on CT morphology features of the tumor margin burr sign,the cavity sign in tumor,the pleural indentation sign,the maximum diameter of the solid portion of tumor>10 mm,solid proportion of tumor>50%and the presence of leisons abutting the pleura,can be used as a predictor of the invasion of visceral pleural invasion in patients with lung adenocarcinoma,with high practical value.关键词
CT形态学征象/肺腺癌/胸膜侵犯/肺肿瘤/危险因素Key words
CT morphological feature/lung adenocarcinoma/pleural invasion/lung tumors/risk factors分类
医药卫生
