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上尿路结石术后并发双J管相关性尿路感染列线图风险预测模型的构建OA

Construction of a risk prediction model for postoperative double J tubule-associated urinary tract infection in patients with upper urinary tract stones

中文摘要英文摘要

目的:探讨上尿路结石病人术后并发双J管相关性尿路感染的危险因素,并构建其列线图风险预测模型.方法:回顾性收集2020年7月—2022年6月某三级甲等综合医院收治的216例上尿路结石并留置双J管病人,根据双J管相关性尿路感染的发病情况将其分为感染组与非感染组,采用单因素分析、Logistic回归分析上尿路结石病人术后并发双J管相关性尿路感染的危险因素,构建列线图风险预测模型并评价该模型的实际效用.结果:上尿路结石病人术后并发双J管相关性尿路感染29例(13.43%).Logistic回归分析结果显示,合并糖尿病、中性粒细胞与淋巴细胞比值(NLR)和肾积水程度是上尿路结石病人术后并发双J管相关性尿路感染的独立危险因素.列线图风险预测模型内部验证结果显示,Hosmer-Lemeshow检验x2=6.981,P=0.639,ROC曲线下面积为0.853[95%CI(0.774,0.934)].结论:构建的列线图风险预测模型具有良好的预警作用,为医护人员早期识别上尿路结石术后并发双J管相关性尿路感染的高危人群,及时采取有效的预防措施降低感染率提供依据.

Objective:To explore the risk factors of postoperative double J tubule-associated urinary tract infection in patients with upper urinary tract stones,and to construct the risk prediction model of the Nomogram.Methods:A total of 216 patients with upper urinary tract stones and double J tube indwelling admitted to a third grade A general hospital from July 2020 to June 2022 were retrospectively collected.The patients were divided into infected group and non-infected group according to whether double-J-tubule-associated urinary tract infection occurred.The risk factors of postoperative double-J-tubule-associated urinary tract infection in patients with upper urinary tract stones were analyzed by univariate analysis and Logistic regression,and the risk prediction model of the Nomogram was constructed and the practical effectiveness of the model was evaluated.Results:There were 29(13.43%)patients with upper urinary tract stones complicated by double J tubule-associated urinary tract infection after operation.Logistic regression analysis showed that diabetes mellitus,neutrophil to lymphocyte ratio(NLR)and the degree of hydronephrosis were independent risk factors for postoperative double J tubule-associated urinary tract infection in patients with upper urinary tract stones.The internal verification results of the Nomogram risk prediction model showed that the Hosmer-Lemeshow test x2=6.981,P=0.639,and the area under the ROC curve was 0.853[95%CI(0.774,0.934)].Conclusions:The constructed Nomogram risk prediction model has a good early warning effect,which provides a basis for medical staff to identify the high-risk population of double J tubule-associated urinary tract infection after upper urinary tract stones operation,and take effective preventive measures in time to reduce the incidence of infection.

杨澜;李先辉;邢业英;田宏艳;袁子璇;谭秀娟;刘娟

416000,吉首大学医学院427000,张家界市人民医院

上尿路结石双J管尿路感染列线图预测模型中性粒细胞与淋巴细胞比值

upper urinary tract stonesdouble J tubeurinary tract infectionNomogramprediction modelneutrophil to lymphocyte ratio

《全科护理》 2024 (008)

1393-1397 / 5

吉首大学校级科研项目,编号:Jdy22090;湖南省卫健委科研项目,编号:D202314058479.

10.12104/j.issn.1674-4748.2024.08.002

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