国际眼科杂志2024，Vol.24Issue(5)：784-789,6.DOI:10.3980/j.issn.1672-5123.2024.5.23
孟德尔随机化在常见眼病中的研究进展
Research progress of Mendelian randomization in ocular diseases
摘要
Abstract
Etiological research is necessary for understanding the occurrence and epidemiological patterns of diseases,and is also a prerequisite for the diagnosis,prevention and treatment of clinical diseases.Mendelian randomization(MR),a method of research that combines genetics and epidemiology,has the advantage of exploring the causal relationship between exposure and disease genetically as well as avoiding confounding factors and reverse causation.Thus,it has been extensively utilized in the etiological study of diseases.This paper reviews the implementation of MR in the research of ocular diseases and provides ideas and approaches for the investigation of related mechanisms as well as the development of intervention strategies.关键词
孟德尔随机化/眼病/病因学研究/因果关系Key words
Mendelian randomization/ocular diseases/etiological study/causality引用本文复制引用
张熙然,袁韦辰,李祥瑞,徐菲儿,赵芳坤..孟德尔随机化在常见眼病中的研究进展[J].国际眼科杂志,2024,24(5):784-789,6.基金项目
辽宁省教育厅2021年度科学研究经费项目(面上项目)(No.LJKZ0773) Foundation item:2021 Scientific Research Project of Liaoning Provincial Department of Education(No.LJKZ0773) （面上项目）
