老年医学与保健2024，Vol.30Issue(2)：297-303,309,8.
左房功能对老年缺血性心肌病患者冠脉搭桥术后远期预后的评估价值
Evaluation value of left atrial function in long-term prognosis of elderly patients with ischemic cardiomyopathy after coronary artery bypass grafting
摘要
Abstract
Objective To investigate the value of left atrial function in evaluating the long-term prognosis of elderly pa-tients with ischemic cardiomyopathy(ICM)after coronary artery bypass grafting(CABG).Methods 131 elderly patients with ICM who received pre-operation cardiac magnetic resonance examination with left ventricular ejection fraction≤35%and under-went CABG in Fuwai Hospital from January 2012 to January 2017 were selected as the study subjects.Their median follow-up time was63.8 months.According to whether the major adverse cardiovascular events(MACE)occurred,they were divided into MACE group and non-MACE group.The baseline characteristics and cardiac magnetic resonance parameters were compared be-tween the two groups.Kaplan-Meier curve was used for survival analysis,and Log-rank test was used for survival comparison.Multivariate COX regression analysis was used to evaluate risk factors for MACE in elderly ICM patients.Results The maxi-mal left atrial volume index(LAVmax/BSA)of the MACE group was higher than that of the non-MACE group,and the left atrial ejection fraction of reservoir(LVEFreservoir)and left atrial ejection fraction of pump(LAEFpump)were lower than those of the non-MACE group,with statistical significance(P＜0.05).The Kaplan-Meier survival curve analysis showed that there was a statistically significant decrease in event free survival rates(P＜0.05)in the LAVmax/BSA≥46.72 mL/m2 group and the LAEFreservoir＜29.94%group.Multivariate COX regression analysis showed that LAEFreservoir[HR 0.964;95%CI(0.94,0.989),P =0.006]was independently associated with the long-term MACE after CABG in elderly ICM patients.Conclusion LAEFreservoir is an independent predictor of long-term MACE in elderly ICM patients after CABG.关键词
老年/缺血性心肌病/心脏磁共振/心房功能/冠脉搭桥Key words
elderly/ischemic cardiomyopathy/cardiac magnetic resonance/atrial function/coronary artery bypass grafting引用本文复制引用
刘千军,陆敏杰,周迪,董影,杨滔,宋卫香,袁勇,尹刚,赵世华,曲新凯..左房功能对老年缺血性心肌病患者冠脉搭桥术后远期预后的评估价值[J].老年医学与保健,2024,30(2):297-303,309,8.基金项目
国家自然科学基金(81971588) （81971588）
中国医学科学院临床与转化医学研究基金(2019XK320063) （2019XK320063）
中国医学科学院中央级公益性科研院所基本科研业务费项目(2019PT310025) （2019PT310025）
