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心房颤动对老年冠心病患者预后的影响

陈芳媛 王敏 毛承誉 俞泉 宋燕琼 顾俊 张俊峰 陈启稚

老年医学与保健2024,Vol.30Issue(2):310-314,329,6.
老年医学与保健2024,Vol.30Issue(2):310-314,329,6.

心房颤动对老年冠心病患者预后的影响

Effects of atrial fibrillation on prognosis of elderly patients with coronary heart disease

陈芳媛 1王敏 1毛承誉 1俞泉 1宋燕琼 1顾俊 1张俊峰 1陈启稚1

作者信息

  • 1. 上海交通大学医学院附属第九人民医院心内科,上海 200001
  • 折叠

摘要

Abstract

Objective To explore the effects of atrial fibrillation(AF)on prognosis of elderly patients with coronary heart disease(CHD).Methods The clinical data of 219 elderly CHD patients admitted to Department of Cardiology,Ninth People's Hospital Affiliated to Medical College of Shanghai Jiaotong University from January 2020 to December 2020 were ret-rospectively analyzed.They were divided into MACE group(n =59)and non-MACE group(n =160)according to the occur-rence of major adverse cardiovascular events(MACE).The general data,serological indexes,echocardiographic parameters and coronary lesions were compared between the two groups.Kaplan-Meier curve was used to analyze the incidence of MACE in elderly CHD patients within 2 years.Cox proportional risk model was used to analyze the influencing factors for MACE in elderly CHD patients.Results Compared with the non-MACE group,the MACE group had lower level of high-density lipoprotein cho-lesterol,higher level of uric acid,and higher proportion of AF,with statistically significant differences(P<0.05).Kaplan-Meier survival analysis showed that the 2-year survival time of AF patients without MACE was shorter than that of the non-AF patients[(17.16±1.03)months vs(21.30±0.48)months,P<0.001].The Cox proportional risk model showed that elevated uric acid level and concomitant AF were risk factors for MACE in elderly CHD patients(P<0.05).Conclusion Elderly CHD patients with high uric acid level or concomitant AF may be more prone to MACE.

关键词

老年人/冠心病/心房颤动/预后

Key words

elderly/coronary heart disease/atrial fibrillation/prognosis

引用本文复制引用

陈芳媛,王敏,毛承誉,俞泉,宋燕琼,顾俊,张俊峰,陈启稚..心房颤动对老年冠心病患者预后的影响[J].老年医学与保健,2024,30(2):310-314,329,6.

老年医学与保健

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