基于国医大师颜德馨教授"衡法"理论管窥肺痿发病机制及治疗OACSTPCD
On the pathogenesis and treatment of pulmonary flaccidity based on the theory of"balance method"by Professor Yan Dexin,a master of traditional Chinese medicine
特发性肺纤维化(IPF)是一种慢性、进行性、不可逆性的间质性肺疾病,病因不明,证候复杂,病情缠绵难愈,多归于中医"肺痿"范畴.基于首届国医大师颜德馨教授"衡法"理论探讨IPF的中医病因病机及治疗,以"气为百病之长,血为百病之胎"为纲,联系"久病必有瘀,怪病必有瘀"的观点,认为发病初期在气,气虚郁而化热伤阴,中后期入血及络,久病累及于阳,瘀既是病理产物又是诱病因素,血瘀贯穿IPF的整个病程.治疗上以调气活血为中心,在IPF早期益气养阴基础上,适用活血化瘀之品,以益气养阴,扶正祛瘀;中期则痰瘀同治,消瘀除痰,使瘀去痰无所倚,痰去瘀无所附;后期温阳散寒与活血化凝并行,以振奋阳气,驱邪外出,使阳复寒去而促瘀化,以达"疏其血气,令其条达而致和平"的目的,为IPF治疗提供了新思路与方法.
Idiopathic pulmonary fibrosis(IPF)is a chronic,progressive and irreversible interstitial lung disease,with un-known etiology,complex syndromes and lingering illness,which mostly belongs to the category of"lung flaccidity"in traditional Chinese medicine.Based on the"balance method"theory of Professor Yan Dexin,the first master of traditional Chinese medi-cine,this paper discusses the etiology,pathogenesis and treatment of IPF in traditional Chinese medicine.Taking"Qi is the length of all diseases,and blood is the fetus of all diseases"as the key link,and connecting with the viewpoint that"there must be blood stasis in a long illness,and there must be blood stasis in a strange disease",it is considered that qi deficiency is de-pressed in the early stage of onset,which turns heat into yin,blood enters the collaterals in the middle and late stage,and yang is involved in a long illness,and blood stasis is both a pathological product and an inducing factor The treatment focuses on regu-lating qi and promoting blood circulation,and on the basis of benefiting qi and nourishing yin at the early stage of IPF,the prod-ucts of promoting blood circulation and removing blood stasis are applied to benefit qi and nourishing yin,strengthen the body re-sistance and dispel blood stasis;In the middle stage,phlegm and blood stasis are treated at the same time,eliminating blood sta-sis and removing phlegm,so that blood stasis and phlegm have nothing to lean on,and phlegm and blood stasis have nothing to attach;In the later stage,warming yang to dispel cold and activating blood circulation to coagulate blood are in parallel,so as to invigorate yang,drive away evil spirits,restore yang to cold and promote blood stasis,so as to achieve the purpose of"dispersing qi and blood,making it smooth and peaceful",which provides new ideas and methods for IPF treatment.
邓祥丽;陈丽娟;杨梅;吴梅;邵梅
云南中医药大学第一临床医学院,云南昆明 650051云南中医药大学第一附属医院,云南昆明 650000
中医学
特发性肺纤维化肺痿衡法气血颜德馨
Idiopathic pulmonary fibrosisPulmonary flaccidityBalance methodQi and bloodYan Dexin
《四川中医》 2024 (002)
6-9 / 4
国家自然科学基金项目(编号:82360922);云南省科技厅科技计划项目-中医联合面上项目[编号:2019FF002(-034)];云南中医药大学第一临床医学院研究生科学研究基金项目(编号:2022YS12).
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