摘要
Abstract
Objective To study the efficacy of modified Yangyin Qingre decoction in treating yin deficiency type of elderly dia-betic nephropathy and the influence on inflammatory factors of C-reactive protein(CRP)and interleukin-6(IL-6).Methods 65elderly patients with yin deficiency type of diabetic nephropathy admitted to hospital from January 2020to December 2022were divided into traditional Chinese medicine group(n=33)and western medicine group(n=32)according to the random number table method.Patients in the western medicine group received conventional western medicine symptomatic treatment,and patients in the traditional Chinese medicine group were given modified Yangyin Qingre decoction on the basis of western medicine group.The therapeutic effect,traditional Chinese medicine syndromes scores,inflammatory factors[CRP,IL-6,tumor necrosis factor-α(TNF-α)]and renal function indicators[serum creatinine(SCr),blood urea nitrogen(BUN),cystatin C(Cys-C)]were compared between both groups.Results The overall effective rate of treatment in the two groups was similar(P＞0.05),but the number of markedly effective cases in traditional Chinese medicine group was more than that in western medicine group(P＜0.05).After treatment,the traditional Chinese medicine syndromes scores,inflammatory factors(IL-6,CRP,TNF-α)and re-nal function indicators(SCr,BUN,Cys-C)were significantly decreased in both groups,and the scores and levels were lower in traditional Chinese medicine group than those in western group(P＜0.01).Conclusion Modified Yangyin Qingre decoction can re-duce the inflammatory response of elderly patients with yin deficiency type of diabetic nephropathy,relieve the symptoms,and ef-fectively improve the renal function of patients,with significant therapeutic efficacy.关键词
养阴清热汤/阴虚型老年糖尿病肾病/生活质量/糖尿病Key words
Yangyin Qingre decoction/Yin deficiency type of elderly diabetic nephropathy/Quality of life/Diabetes melli-tus分类
医药卫生
