陕西中医2024，Vol.45Issue(5)：630-633,4.DOI:10.3969/j.issn.1000-7369.2024.05.012
益气养血方联合促红素治疗糖尿病肾病腹膜透析患者肾性贫血临床观察
Clinical efficacy of Yiqi Yangxue prescription combined with erythropoietin in the treatment of renal anemia in patients undergoing peritoneal dialysis for diabetic nephropathy
摘要
Abstract
Objective:To investigate the clinical efficacy of Yiqi Yangxue prescription combined with erythropoi-etin in the treatment of renal anemia in patients undergoing peritoneal dialysis(PD)for diabetic nephropathy.Methods:A totalof 60 patients with renal anemia who underwent PD for diabetic nephropathy were selected,according to ran-dom number table method divided into observation group and control group 30 cases each.The control group was treated with routine erythropoietin,while the observation group was treated with Yiqi Yangxue prescription on the basis of the control group.Efficacy in the two groups was evaluated.Anemia indicators,peritoneal function indicators and adverse reactions were compared between the groups.Results:TCM syndrome score after treatment,the observa-tion group was obviously lower than the control group,and the clinical curative effect(90.00%)of the observation group was obviously higher than that of control group(66.67%)(P<0.05).Two groups before treatment of ane-mia indicators[hemoglobin(Hb),hematocrit(Hct),RBC count(RBC)]was no difference(P>0.05),the observa-tion group after treatment of Hb,Hct,RBC level were higher than the control group(P<0.05).Before treatment,two groups of peritoneal function index level[PD(Kt/V),blood urea clearance index of dialysate and creatinine in the blood concentration ratio(D/Pcr),PD ultrafiltration(UF)]was no difference(P>0.05),after treatment,the observation group of Kt/V,D/Pcr,UF levels higher than the control group(P<0.05).Observation group of adverse reactions to the total incidence of 6.67%,the control group was 23.33%,which showed no difference(P>0.05).Conclusion:Applying Yiqi Yangxue prescription combined with erythropoietin to treat renal anemia in patients under-going PD for diabetic nephropathy can effectively alleviate anemia symptoms,and improve the therapeutic effect,ane-mia related indicators and peritoneal function,without increasing the risk of adverse reactions.关键词
糖尿病肾病/益气养血方/促红素/腹膜透析/肾性贫血Key words
Diabetic nephropathy/Yiqi Yangxue prescription/Erythropoietin/Peritoneal dialysis/Renal anemia分类
医药卫生引用本文复制引用
张志辉,束永兵..益气养血方联合促红素治疗糖尿病肾病腹膜透析患者肾性贫血临床观察[J].陕西中医,2024,45(5):630-633,4.基金项目
安徽省重点研究与开发计划项目(202104J07020014) （202104J07020014）
