临床医学工程2024，Vol.31Issue(5)：599-600,2.DOI:10.3969/j.issn.1674-4659.2024.05.0599
左甲状腺素钠对妊娠合并甲减患者甲状腺功能及分娩结局的影响
Impact of Levothyroxine Sodium on Thyroid Function and Delivery Outcomes in Pregnancy Patients with Hypothyroidism
蔡燕瑜 1官青青 2黄征芳1
作者信息
- 1. 厦门市翔安区妇幼保健院孕产保健科,福建厦门 361100
- 2. 厦门市第五医院产科,福建厦门 361101
- 折叠
摘要
Abstract
Objective To explore the impact of levothyroxine sodium on thyroid function and delivery outcomes in pregnancy patients with hypothyroidism.Methods 220 pregnancy patients with hypothyroidism admitted to our hospital from January 2022 to January 2023 were rsndomly divided into two groups,with 110 cases in each group.The control group was given daily life guidance,while the study group was treated with levothyroxine sodium on the basis of the control group.The thyroid function indicators,positive rates of anti thyroid peroxidase antibody(TPOAb)and anti thyroid globulin antibody(TGAb),incidence of adverse delivery outcomes,and incidence of adverse reactions were compared between the two groups.Results After treatment,the TSH level of the study group was lower than that of the control group,and the FT3 and FT4 levels were higher than those of the control group(P＜0.05).After treatment,the positive rates of TPOAb and TGAb in the study group were lower than those in the control group(P＜0.05).The incidence of adverse delivery outcomes in the study group was lower than that in the control group(P＜0.05).Both groups did not have serious adverse reactions.Conclusions Leftothyroxine sodium can effectively improve the thyroid function and avoid the adverse delivery outcomes in pregnancy patients with hypothyroidism,with higher safety.关键词
甲状腺功能减退/妊娠/左甲状腺素钠/甲状腺功能/分娩结局Key words
Hypothyroidism/Pregnancy/Left thyroxine sodium/Thyroid function/Delivery outcome分类
医药卫生引用本文复制引用
蔡燕瑜,官青青,黄征芳..左甲状腺素钠对妊娠合并甲减患者甲状腺功能及分娩结局的影响[J].临床医学工程,2024,31(5):599-600,2.
