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不同频率重复经颅磁刺激联合药物治疗癫痫的效果研究

王丹慧 崔滨 孙丽霞 李青华 王松林 彭斐斐 于江涛 许自强

临床医学工程2024,Vol.31Issue(5):529-530,2.
临床医学工程2024,Vol.31Issue(5):529-530,2.DOI:10.3969/j.issn.1674-4659.2024.05.0529

不同频率重复经颅磁刺激联合药物治疗癫痫的效果研究

Study on Effect of Different Frequencies of Repetitive Transcranial Magnetic Stimulation Combined with Drugs in the Treatment of Epilepsy

王丹慧 1崔滨 2孙丽霞 1李青华 1王松林 1彭斐斐 1于江涛 1许自强1

作者信息

  • 1. 许昌市中心医院神经内科,河南许昌 461000
  • 2. 航空总医院神经外科,北京 100012
  • 折叠

摘要

Abstract

Objective To explore the effect of different frequencies of repetitive transcranial magnetic stimulation(rTMS)combined with drugs in the treatment of epilepsy.Methods 106 epilepsy patients admitted to our hospital from March 2020 to March 2021 were randomly divided into observation group(53 cases,5.0 Hz rTMS combined with drugs)and control group(53 cases,1.0 Hz rTMS combined with drugs).The efficacy,EEG indicators,cognitive function and quality of life were compared between groups.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After 4 weeks of treatment,the EEG sharp wave number and sharp wave duration of the observation group were lower than those of the control group(P<0.05).After 4 weeks of treatment,the scores of Mini Mental State Examination(MMSE)and the Quality of Life in Epilepsy(QOLIE-31)in the observation group were higher than those in the control group(P<0.05).Conclusions Compared with 1.0 Hz rTMS,5.0 Hz rTMS combined with drugs has significant effect in the treatment of epilepsy,which can effectively improve patients'EEG,cognitive function and quality of life.

关键词

不同频率/重复经颅磁刺激/癫痫/脑电图

Key words

Different frequencies/Repetitive transcranial magnetic stimulation/Epilepsy/Electroencephalogram

分类

医药卫生

引用本文复制引用

王丹慧,崔滨,孙丽霞,李青华,王松林,彭斐斐,于江涛,许自强..不同频率重复经颅磁刺激联合药物治疗癫痫的效果研究[J].临床医学工程,2024,31(5):529-530,2.

临床医学工程

1674-4659

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