临床医学工程2024，Vol.31Issue(5)：539-540,2.DOI:10.3969/j.issn.1674-4659.2024.05.0539
喹硫平联合丁螺环酮治疗精神分裂症的效果
Effect of Quetiapine Combined with Buspirone in the Treatment of Schizophrenia
摘要
Abstract
Objective To analyze the effect of quetiapine combined with buspirone in the treatment of patients with schizophrenia(SCH).Methods 100 SCH patients admitted to our hospital from April 2020 to March 2023 were selected and divided into observation group and control group according to odd even order.The control group was treated with quetiapine,while the observation group was treated with quetiapine combined with buspirone.The symptom score,serum indicator levels and quality of life were compared between the two groups.Results After treatment,the PANSS score of the observation group was lower than that of the control group(P＜0.05).After treatment,the glial-derived neurotrophic factor(GDNF),brain derived neurotrophic factor(BDNF)and 5-hydroxytryptamine(5-HT)levels of the observation group were higher than those of the control group(P＜0.05).After treatment,the GQOLI-74 score of the observation group was higher than that of the control group(P＜0.05).Conclusions Quetiapine combined with buspirone can relieve the clinical symptoms,regulate the neurotransmitter levels,and improve the quality of life of SCH patients.关键词
喹硫平/丁螺环酮/精神分裂症Key words
Quetiapine/Buspirone/Schizophrenia分类
医药卫生引用本文复制引用
胡广旭,赵云东,孙连风..喹硫平联合丁螺环酮治疗精神分裂症的效果[J].临床医学工程,2024,31(5):539-540,2.基金项目
河南省医学科技攻关计划联合共建项目(LHGJ20200528) （LHGJ20200528）
