中国医疗设备2024，Vol.39Issue(4)：8-12,5.DOI:10.3969/j.issn.1674-1633.2024.04.002
一种表征可吸收胶原蛋白材料孔结构的方法研究
Method for Characterizing the Porous Structure of Absorbable Collagen Materials
摘要
Abstract
Objective To develop a method for characterizing the microstructure of absorbable collagen materials,and analyze their porosity and pore size.Methods Field emission scanning electron microscope(SEM)was used,images of non-gold-sprayed samples and gold-sprayed samples were captured at different acceleration voltages.The obtained SEM images were analyzed for porosity and pore size by using Image J software,and the availability of the results was verified.Results The clear SEM images were obtained by using a lower acceleration voltage for non-gold-sprayed samples.After gold spraying,the ability to withstand voltage was significantly improved,and the clear SEM images could be obtained even at higher acceleration voltages.The obtained SEM images were analyzed for pore size and porosity using Image J software.Among them,the average porosity was 50.9%and the average pore size was 11.9 μm.The dispersion coefficient of porosity was 8.6%.and the dispersion coefficient of pore size was 6.7%.Conclusion The combination of field emission SEM and Image J software is an effective method for characterizing the porous structure of absorbable collagen materials,which can solve the issue of missing methods in relevant standards.关键词
场发射扫描电子显微镜/可吸收胶原蛋白/孔结构/Image J软件Key words
field emission scanning electron microscope/absorbable collagen/porous structure/Image J software分类
基础医学引用本文复制引用
王常斌,王秀秀,陈洪建,艾冲冲,万敏,卢文博..一种表征可吸收胶原蛋白材料孔结构的方法研究[J].中国医疗设备,2024,39(4):8-12,5.基金项目
国家重点研发计划(2022YFC2409801) （2022YFC2409801）
山东省医疗器械和药品包装检验研究院课题(ZX202118). （ZX202118）
