中国当代儿科杂志2024，Vol.26Issue(4)：432-436,5.DOI:10.7499/j.issn.1008-8830.2312016
莫西沙星治疗超早产儿人型支原体脑膜炎1例
Moxifloxacin treatment for Mycoplasma hominis meningitis in an extremely preterm infant
毛玮莹 1蓝江儿 2甘明宇 3张迅捷 2俞蕙 4胡黎园 1张蓉 1曹云 1肖蜜黎1
作者信息
- 1. 国家儿童医学中心/复旦大学附属儿科医院新生儿科,上海 201102
- 2. 国家儿童医学中心/复旦大学附属儿科医院临床药学部,上海 201102
- 3. 国家儿童医学中心/复旦大学附属儿科医院儿科研究院,上海 201102
- 4. 国家儿童医学中心/复旦大学附属儿科医院感染科,上海 201102
- 折叠
摘要
Abstract
The patient,a male newborn,was admitted to the hospital 2 hours after birth due to prematurity(gestational age 27+5 weeks)and respiratory distress occurring 2 hours postnatally.After admission,the infant developed fever and elevated C-reactive protein levels.On the fourth day after birth,metagenomic next-generation sequencing of cerebrospinal fluid indicated a positive result for Mycoplasma hominis(9 898 reads).On the eighth day,a retest of cerebrospinal fluid metagenomics confirmed Mycoplasma hominis(56 806 reads).The diagnosis of purulent meningitis caused by Mycoplasma hominis was established,and the antibiotic treatment was switched to moxifloxacin[5 mg/(kg·day)]administered intravenously for a total of 4 weeks.After treatment,the patient's cerebrospinal fluid tests returned to normal,and he was discharged as cured on the 76th day after birth.This article focuses on the diagnosis and treatment of neonatal Mycoplasma hominis purulent meningitis,introducing the multidisciplinary diagnosis and treatment of the condition in extremely preterm infants.[Chinese Journal of Contemporary Pediatrics,2024,26(4):432-436]关键词
化脓性脑膜炎/人型支原体/莫西沙星/超早产儿Key words
Purulent meningitis/Mycoplasma hominis/Moxifloxacin/Extremely preterm infant引用本文复制引用
毛玮莹,蓝江儿,甘明宇,张迅捷,俞蕙,胡黎园,张蓉,曹云,肖蜜黎..莫西沙星治疗超早产儿人型支原体脑膜炎1例[J].中国当代儿科杂志,2024,26(4):432-436,5.
