临床医学工程2024，Vol.31Issue(5)：571-572,2.DOI:10.3969/j.issn.1674-4659.2024.05.0571
芪苈强心胶囊联合沙库巴曲缬沙坦对慢性心力衰竭患者NT-proBNP水平及心功能的影响
Impact of Qili Qiangxin Capsules and Sacubitril Valsartan on NT-proBNP Level and Cardiac Function in Patients with Chronic Heart Failure
母春丽 1刘伟 1赵伟 1王福芹1
作者信息
- 1. 山东省单县中医医院心内科,山东菏泽 274300
- 折叠
摘要
Abstract
Objective To explore the effect of Qili Qiangxin capsule combined with sacubitril valsartan in the treatment of chronic heart failure(CHF).Methods 116 CHF patients admitted to our hospital from January 2021 to January 2023 were randomly divided into control group(58 cases)and observation group(58 cases).The control group was treated with sacubitril valsartan sodium tablets,while the observation group was treated with Qili Qiangxin capsules on the basis of the control group.Both groups were treated continuously for 12 weeks.The clinical efficacy,NT-proBNP levels,cardiac function and adverse reactions of the two groups were compared.Results The total effective rate of treatment in the observation group was 91.38％,higher than 77.59％in the control group(P＜0.05).After treatment,the LVEF of the observation group was higher than that of the control group,and the LVEDD,LVESD and NT-proBNP were lower than those of the control group(P＜0.05).No statistical difference was found in the incidence of adverse reactions between the two groups(P＞0.05).Conclusions Qili Qiangxin capsules combined with sacubitril valsartan has significant effect in the treatment of CHF patients,can improve the cardiac function indicators,and reduce the NT-proBNP level,which is safe,reliable and worthy of promotion and application.关键词
慢性心力衰竭/芪苈强心胶囊/沙库巴曲缬沙坦/NT-proBNP水平/心功能Key words
Chronic heart failure/Qili Qiangxin Capsule/Sacubitril valsartan/NT-proBNP level/Cardiac function分类
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母春丽,刘伟,赵伟,王福芹..芪苈强心胶囊联合沙库巴曲缬沙坦对慢性心力衰竭患者NT-proBNP水平及心功能的影响[J].临床医学工程,2024,31(5):571-572,2.
