中国医学创新2024，Vol.21Issue(12)：144-148,5.DOI:10.3969/j.issn.1674-4985.2024.12.033
LISA技术与INSURE技术治疗早产儿呼吸窘迫综合征的效果比较
Comparison of the Effect of LISA Technique and INSURE Technique in the Treatment of Respiratory Distress Syndrome of Preterm Infants
摘要
Abstract
Objective:To discuss the application effect of two different administration methods of less invasive surfactant administration(LISA)and intubation-surfactant-extubate(INSURE)on respiratory distress syndrome(RDS)in preterm infants.Method:A total of 55 children with NRDS treated in Jiangxi Provincial Children's Hospital from January 1,2019 to August 31,2022 were divided into LISA group(given LISA technique,n=29)and INSURE group(given INSURE technique,n=26)by random number table method.Treatment related indexes and complications were compared between the two groups.Result:There was no significant difference in the utilization rate of secondary Calf Pulmonary Surfactant(CPS)between the two groups(P>0.05).The treatment rate of invasive mechanical ventilation within 72 h in LISA group was lower than that in INSURE group,and the mechanical ventilation time,total oxygen use time and hospital stay were shorter than those in INSURE group,the differences were statistically significant(P<0.05).The incidences of broncho-pulmonary dysplasia(BPD)and retinopathy of prematurity(ROP)in LISA group were lower than those in INSUR group,the differences were statistically significant(P<0.05),but there were no significant differences in the incidences of other complications between the two groups(P>0.05).Conclusion:Compared with INSURE technique,LISA technique can effectively reduce the mechanical ventilation rate,shorten the oxygen use time,and reduce the occurrence of BPD and ROP in the treatment of RDS in preterm infants.关键词
早产儿/呼吸窘迫综合征/微创注入肺表面活性物质/气管插管-肺表面活性物质-拔管Key words
Preterm infants/Respiratory distress syndrome/Less invasive surfactant administration/Intubation-surfactant-extubate引用本文复制引用
刘祥英,何帆,吴金星,魏文超,晏长红,王巧芳,吴丹,刘春子..LISA技术与INSURE技术治疗早产儿呼吸窘迫综合征的效果比较[J].中国医学创新,2024,21(12):144-148,5.基金项目
江西省卫生健康委员会科技计划项目(20203660) （20203660）
