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PARK7基因对氧化应激的调控研究进展

樊庆灿 王倩倩 杨虎 郑路程 胡威

中国畜牧杂志2024,Vol.60Issue(5):8-12,5.
中国畜牧杂志2024,Vol.60Issue(5):8-12,5.DOI:10.19556/j.0258-7033.20230608-06

PARK7基因对氧化应激的调控研究进展

Research Progress on the Regulation of Park7 Geneon Oxidative Stress

樊庆灿 1王倩倩 2杨虎 1郑路程 2胡威1

作者信息

  • 1. 宜春学院生命科学与资源环境学院,江西宜春 336000
  • 2. 宜春学院生命科学与资源环境学院,江西宜春 336000||甘肃农业大学动物医学院,甘肃兰州 730000
  • 折叠

摘要

Abstract

Under the large-scale breeding mode,the livestock inevitably faces various adverse factors in the growth process,which leads to oxidative stress in the body and seriously affects their growth and development.There are a variety of antioxidant factors in livestock and poultry to cope with oxidative stress.Among them,Parkinson's disease associated protein 7(PARK7)gene is one of the important regulators in cellular oxidative stress.PARK7 senses oxidative stress signals through the oxidation level of its own cysteine,and promotes the generation of antioxidant enzymes through Nrf2,erk1/2,and pi3k/akt pathways to improve the antioxidant capacity of cells,thereby alleviating the damage caused by oxidative stress.

关键词

PARK7/DJ-1/氧化应激/Nrf2通路

Key words

PARK7/DJ-1/Oxidative stress/Nrf2 pathway

分类

农业科技

引用本文复制引用

樊庆灿,王倩倩,杨虎,郑路程,胡威..PARK7基因对氧化应激的调控研究进展[J].中国畜牧杂志,2024,60(5):8-12,5.

基金项目

江西省教育厅科学技术项目(GJJ211628) (GJJ211628)

宜春学院2021年第二批校级大学生创新创业训练计划项目(447) (447)

中国畜牧杂志

OA北大核心CSTPCD

0258-7033

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