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高产虾青素的红法夫酵母菌株选育研究进展

孙克诚 胡丹丹 袁文华 王令 周静静 王梓旭

中国畜牧杂志2024,Vol.60Issue(5):12-17,6.
中国畜牧杂志2024,Vol.60Issue(5):12-17,6.DOI:10.19556/j.0258-7033.20230808-03

高产虾青素的红法夫酵母菌株选育研究进展

Research Progress on Breeding High-Yield Strains of Astaxanthin-Producting Phaffia rhodozyma

孙克诚 1胡丹丹 1袁文华 1王令 1周静静 1王梓旭1

作者信息

  • 1. 安佑生物科技集团股份有限公司,江苏太仓 215437
  • 折叠

摘要

Abstract

Astaxanthin(3,3'-dihydroxy-β,β'-carotene-4,4'-dione),a potent antioxidant,possesses diverse physiological functions including anti-inflammatory,anti-apoptotic,and anticancer properties.Natural astaxanthin is the preferred choice of consumers over chemically synthesized alternatives due to its superior biological activity,utilization efficiency,and enhanced safety profile.Phaffia rhodozyma,which can utilize a variety of carbon sources and has a short cultivation period,is an ideal natural source of astaxanthin.However,the limited yield of astaxanthin during production poses a hindrance to the widespread application of Phaffia rhodozyma in the industry.Consequently,this article provides an overview of the main methods in advancing the production of astaxanthin in Phaffia rhodozyma,encompassing mutagenesis breeding,optimization of culture conditions and growth media,and amelioration of the biological synthetic pathways.The aim is to lay a theoretical foundation for the application of Phaffia rhodozyma in the industry and the enhancement of astaxanthin production.

关键词

红法夫酵母/虾青素/诱变育种/工艺优化/生物合成

Key words

Phaffia rhodozyma/Astaxanthin/Mutagenesis breeding/Process optimization/Biosynthesis

分类

农业科技

引用本文复制引用

孙克诚,胡丹丹,袁文华,王令,周静静,王梓旭..高产虾青素的红法夫酵母菌株选育研究进展[J].中国畜牧杂志,2024,60(5):12-17,6.

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