中国药科大学学报2024，Vol.55Issue(2)：202-208,7.DOI:10.11665/j.issn.1000-5048.2023122704
小叶爬崖香中苷类化合物的研究
Study of glycosides from Piper sintenense Hatusima
涂鹏煌 1姚志仁 1金美玲 1宁冠宇 1黄亚萍 1潘珂 2殷志琦1
作者信息
- 1. 中国药科大学中药学院中药制药系,南京 211198
- 2. 中国药科大学中药学院天然药物化学系,南京 211198
- 折叠
摘要
Abstract
In order to investigate the chemical constituents of glycosides in Piper sintenense Hatusima,column chromatographic techniques such as silica gel,ODS,MCI GEL CHP20P,Sephadex LH-20,and semi-preparative high performance liquid chromatography were used to afford nine glycosides from the n-butanol part of the 95%ethanol extract of Piper sintenense Hatusima.Based on the physicochemical properties and NMR data,the above compounds were identified as(2S)-2-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1-propanone-2-O-β-D-glucopyranoside(1),2-phenylethyl β-D-glucopyranoside(2),benzyl α-L-arabinopyranosyl-(1''→6')-β-D-glucopyranoside(3),benzyl β-D-xylopyanosyl-(1''→6')-β-D-glucopyranoside(4),phenethyl β-D-apiofuranosyl-(1''→ 2')-β-D-glucopyranoside(5),salidroside(6),phenethanol β-D-xylopyanosyl-(1''→6')-β-D-glucopyranoside(7),(Z)-hexenyl-O-α-L-arabinopyranosyl-(1''→6')-O-β-D-glucopyranoside(8),(Z)-hexenyl-O-β-D-xylopyanosyl-(1''→6')-O-β-D-glucopyranoside(9).Compound 1 was identified as a new compound,and compounds 3-9 were isolated from the genus Piperfor the first time.关键词
胡椒属/小叶爬崖香/化学成分/糖苷/分离鉴定Key words
Piper spp./Piper sintenense Hatusima/chemical constituents/glycoside/isolation and identification分类
医药卫生引用本文复制引用
涂鹏煌,姚志仁,金美玲,宁冠宇,黄亚萍,潘珂,殷志琦..小叶爬崖香中苷类化合物的研究[J].中国药科大学学报,2024,55(2):202-208,7.
