中国畜牧杂志2024，Vol.60Issue(5)：23-33,11.DOI:10.19556/j.0258-7033.20230310-07
微丝调控卵母细胞减数分裂成熟的分子机制研究进展
Research Progress on Molecular Mechanism of Microfilament Regulating Meiotic Maturation of Oocytes
摘要
Abstract
Oocytes undergo two rounds of meiosis before fusing with sperm to form a zygote.In contrast to mitosis,both meiotic divisions are asymmetric and eventually generate one large volume of haploid oocytes with totipotent and two small volumes of doomed degenerate polar bodies.Actin filaments,as cytoskeletons in oocytes,are importantly linked to the biological events during division undergoing vesicle translocation,nuclear localization,spindle migration and anchoring,polar body extrusion,and chromosome segregation.This review uses mammals as a model to summarize the critical regulatory mechanisms and signaling pathways of actin in the meiotic maturation of oocytes,in order to provide a reference for further study on the regulation mechanism of oocyte maturation process.关键词
卵母细胞/减数分裂/肌动蛋白/哺乳动物Key words
Oocyte/Meiosis/Actin/Mammals分类
农业科技引用本文复制引用
张旭林,刘理想,范冰峰,张颖,许保增..微丝调控卵母细胞减数分裂成熟的分子机制研究进展[J].中国畜牧杂志,2024,60(5):23-33,11.基金项目
国家自然科学基金面上项目(32172739) （32172739）
吉林省实验动物领域创新研究项目(20230505045ZP) （20230505045ZP）
