中国内镜杂志2024，Vol.30Issue(4)：1-6,6.DOI:10.12235/E20230564
影响腰椎间盘突出症患者经皮椎间孔镜下椎间盘切除术治疗效果的相关因素分析
Associated factors affecting the therapeutic effect of percutaneous transforaminal endoscopic discectomy in patients with lumbar disc herniation
摘要
Abstract
Objective To analyze the related factors affecting the therapeutic effect of percutaneous transforaminal endoscopic discectomy(PTED)in patients with lumbar disc herniation(LDH)based on Logistic analysis.Methods 310 LDH patients from March 2019 to August 2022 were included in the study,all of them were treated with PTED.Clinical data of the patients were retrospectively collected.All patients were followed up for 1 year,of which 259 cases had excellent therapeutic effects and were included in the excellent group,and 51 cases with good or poor efficacy were included in the non-excellent group.The factors influencing the curative effect of PTED in patients with LDH were analyzed by univariate analysis and multivariate Logistic regression analysis.Results 310 cases of LDH were treated by PTED.During 1-year follow-up,259 cases had excellent curative effect,and the rate of excellent was 83.55％.Compared with the excellent group,the proportions of age>50 years,the pain presented as back and leg pain,the course of LDH>1 year,lateral recess stenosis,annulus fibrosus rupture,Modic change,the working mode of weight-bearing or long-term fixed posture,the Pfirrmann grade of disc degeneration Ⅲ～Ⅳ were higher(P<0.05).The multivariate Logistic regression analysis showed that age>50 years old(O(R) = 1.022,95％CI:1.006～1.038),pain manifested as lower back and leg pain(O(R) = 1.059,95％CI:1.036～1.081),lateral recess stenosis(O(R) = 1.069,95％CI:1.020～1.120),and working mode in a weight-bearing or long-term fixed position(O(R) = 1.064,95％CI:1.025～1.104)were non excellent risk factors for PTED treatment efficacy in LDH patients(P<0.05).Conclusion The curative effect rate of patients with LDH by PTED for 1-year follow-up is 83.55％,there are many factors that affect the efficacy,such as age>50 years,pain manifested as lower back and leg pain,lateral recess stenosis,working mode in a weight-bearing or long-term fixed position.Corresponding intervention measures could be taken clinically based on this.关键词
腰椎间盘突出症/经皮椎间孔镜下椎间盘切除术/疗效/Logistic分析/影响因素Key words
lumbar disc herniation/percutaneous transforaminal endoscopic discectomy/therapeutic effect/Logistic analysis/influence factors分类
医药卫生引用本文复制引用
张陇豫,康晓乐,任敬佩,贾治伟..影响腰椎间盘突出症患者经皮椎间孔镜下椎间盘切除术治疗效果的相关因素分析[J].中国内镜杂志,2024,30(4):1-6,6.基金项目
国家自然科学基金(No:81601948) （No:81601948）
