中国医药科学2024，Vol.14Issue(7)：176-180,5.DOI:10.20116/j.issn2095-0616.2024.07.40
脾动脉栓塞治疗创伤性脾破裂的临床特征及影响因素分析
Clinical characteristics and influencing factors of splenic artery embolization in the treatment of traumatic splenic rupture
摘要
Abstract
Objective To evaluate the clinical efficacy of splenic artery embolization in the treatment of traumatic splenic rupture,and explore the risk factors that affect treatment outcomes and complications.Methods Retrospective analysis was conducted on the clinical data of 63 cases of traumatic closed splenic rupture treated with splenic artery embolization at Taizhou Municipal Hospital and Xiamen Chang Gung Hospital from January 1,2015 to January 1,2022,with their clinical characteristics and factors affecting prognosis analyzed,and predictive models established.Results Among 63 cases of traumatic closed splenic rupture treated with splenic artery embolization,60 cases were successfully rescued,2 cases died,and 1 case underwent laparotomy after interventional surgery,with a success rate of 95.24%.Complications occurred in 15 cases during the treatment process.According to ROC curve analysis,when the injury severity score(ISS)was≥27.5 points,it was most sensitive to the diagnosis of complications,with a sensitivity of 46.70%and a specificity of 77.10%;univariate analysis showed significant differences in the incidence of complications among hemoglobin(Hb),activated partial thromboplastin time(APTT),and American association for the surgery of trauma(AAST)splenic injury scale(P<0.05);multivariate analysis showed that APTT and Hb were independent factors affecting the incidence of complications(P<0.05);the nomogram prediction model showed that the likelihood of complications occurring in APTT>36 s was 17.936-fold higher than that occurring in APTT≤36 s,and the risk of complications in Hb[130,175)g/L was only 6%of that in Hb[70,90)g/L.Conclusion When ISS is≥27.5 points,it is the most sensitive for the diagnosis of complications.Hb,APTT,and AAST are the influencing factors for the occurrence of complications in splenic artery embolization treatment of traumatic splenic rupture,and APTT and Hb levels are independent factors affecting the occurrence of complications.关键词
脾动脉栓塞/脾破裂/危险因素/多因素分析Key words
Splenic artery embolization/Splenic rupture/Risk factor/Multivariate analysis分类
医药卫生引用本文复制引用
李敏献,王博,周龙..脾动脉栓塞治疗创伤性脾破裂的临床特征及影响因素分析[J].中国医药科学,2024,14(7):176-180,5.基金项目
2021年浙江省卫生健康科技计划项目(2021KY397). （2021KY397）
