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基于决策树模型的内镜逆行胰胆管造影术后胆总管结石复发的研究

张振宇 孙艳 耿利利 崔立阳 应丽娜 李瑞芳 张骏

中国内镜杂志2024,Vol.30Issue(4):36-44,9.
中国内镜杂志2024,Vol.30Issue(4):36-44,9.DOI:10.12235/E20230373

基于决策树模型的内镜逆行胰胆管造影术后胆总管结石复发的研究

A decision tree model-based investigation of the recurrence of calculus of common bile duct following endoscopic retrograde cholangiopancreatography

张振宇 1孙艳 2耿利利 1崔立阳 2应丽娜 2李瑞芳 2张骏1

作者信息

  • 1. 蚌埠医科大学 研究生院,安徽 蚌埠 233030
  • 2. 浙江省人民医院 浙江省胃肠病学重点实验室,浙江 杭州 310014
  • 折叠

摘要

Abstract

Objective The decision tree model was utilized to investigate the risk factors and recurrence probability of calculus of common bile duct following endoscopic retrograde cholangiopancreatography(ERCP).Methods Clinical data of 500 patients who underwent ERCP with calculus of common bile duct from January 2016 to December 2020 were retrospectively analyzed.Decision tree and Logistic regression models were separately established,and the receiver operator characteristic curve(ROC curve)were established,area under the curve(AUC),sensitivity,and specificity were used to evaluate the predictive performance of both models.Independent risk factors of recurrence for calculus of common bile duct after ERCP were identified,and the models were utilized to predict the risk of recurrence in patients.Results The decision tree analysis revealed that the history of choledocholithotomy(P = 0.000),common bile duct diameter>1.60 cm(P = 0.000),and history of cholecystectomy(P = 0.004)were significant risk factors for calculus of common bile duct recurrence after ERCP.Furthermore,Logistic regression analysis identified independent risk factors for calculus of common bile duct recurrence after ERCP,including the history of cholecystectomy(P = 0.003),history of choledocholithotomy(P = 0.000),common bile duct diameter>1.60 cm(P = 0.000),number of stones≥2(P = 0.001),and biliary stent(P = 0.038),albumin level≥40.5 g/L(P = 0.026)as a protective factor.Compared to the Logistic regression model(93.3%),the decision tree model had an overall accuracy of 92.2%,an AUC of 0.890(95%CI:0.839~0.940)and 0.926(95%CI:0.887~0.964),sensitivity of 87.0%and 85.3%,and specificity of 81.0%and 89.2%.Conclusion The history of choledocholithotomy,common bile duct diameter>1.60 cm,and cholecystectomy significantly contribute to the risk of stone recurrence.The decision tree model offers a simple and user-friendly approach that enhances the prediction accuracy of stone patients'recurrence risk.It can serve as a valuable tool for screening and targeted prevention strategies aimed at high-risk groups susceptible to calculus of common bile duct recurrence after ERCP.

关键词

胆总管结石/内镜逆行胰胆管造影术(ERCP)/决策树/预测模型

Key words

calculus of common bile duct/ERCP/decision tree/prediction model

分类

医药卫生

引用本文复制引用

张振宇,孙艳,耿利利,崔立阳,应丽娜,李瑞芳,张骏..基于决策树模型的内镜逆行胰胆管造影术后胆总管结石复发的研究[J].中国内镜杂志,2024,30(4):36-44,9.

中国内镜杂志

OACSTPCD

1007-1989

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