摘要
Abstract
Objective Compare the application effects of laparoscopic nephron sparing surgery(LNSS)with transperitoneal and retroperitoneal approaches.Methods 100 patients who underwent LNSS from January 2018 to December 2022 were selected and divided into two groups according to different surgical methods:53 patients in the transperitoneal laparoscopic nephron sparing surgery(TLNSS)group and 47 patients in the retroperitoneal laparoscopic nephron sparing surgery(RLNSS)group.The perioperative treatment indexes,renal function indicators before and after treatment,clinical treatment efficacy,and incidence of complications were compared between the two groups.Result The surgical time,warm ischemia time,intestinal function recovery time,and renal artery occlusion time of the TLNSS group were significantly longer than those of the RLNSS group,the differences were statistically significant(P＜0.05).The intraoperative bleeding volume,drainage tube removal time,and hospitalization time of the TLNSS group were not statistically significant compared to the RLNSS group,the differences were not statistically significant(P＞0.05).After surgery,serum cholinesterase(ChE)in both groups increased compared to before surgery,while blood urea nitrogen(BUN)and serum creatinine(Scr)in both groups decreased compared to before surgery,ChE in the TLNSS group was significantly lower than that in the RLNSS group,while BUN and Scr in the TLNSS group were significantly higher than those in the RLNSS group,the differences were statistically significant(P＜0.05).The clinical treatment of disease control rate(DCR)and overall response rates(ORR)in the TLNSS group were significantly lower than those of the RLNSS group,the differences were statistically significant(P＜0.05).The incidence of total complications in the TLNSS group was significantly higher than that in the RLNSS group,the differences was statistically significant(P＜0.05).Conclusion The retroperitoneal approach of LNSS can significantly shorten surgical and warm ischemia time,promote intestinal and renal function recovery,improve efficacy,and reduce the risk of complications.It is worthy of clinical application.关键词
肾肿瘤切除术/经腹腔入路/经腹膜后入路/肾功能/疗效Key words
renal tumor resection/transperitoneal approach/retroperitoneal approach/renal function/curative effect分类
医药卫生
