中国医药科学2024，Vol.14Issue(7)：30-34,5.DOI:10.20116/j.issn2095-0616.2024.07.07
基于"无湿不成泻"探讨化湿法调节肠道菌群治疗腹泻型肠易激综合征
Exploration of the treatment of diarrhea-predominant irritable bowel syndrome by regulating intestinal microflora through the dampness-resolving method based on the principle of"no dampness,no diarrhea"
摘要
Abstract
Diarrhea-predominant irritable bowel syndrome(IBS-D)is a common chronic functional intestinal lesion in clinical practice,with diarrhea as the main symptom.It is characterized by recurrent attacks,a long course of disease,no organic lesions,and prominent psychological factors.It belongs to the categories of"diarrhea"and"abdominal pain"in traditional Chinese medicine.The"Essential Readings for Medical Professionals"states that"no dampness,no diarrhea",indicating that the main pathological factor of this disease is dampness and turbidity.Therefore,the basic method of treating this disease is to dissolve dampness.Research has shown that the disorder of intestinal microflora is an important feature of the occurrence and development of IBS-D,and Chinese herbal medicine and compound prescriptions for dissolving dampness can help restore the balance and homeostasis of intestinal microflora.Based on the pathological core of"no dampness,no diarrhea",this article explores the traditional Chinese medicine pathogenesis of the treatment of IBS-D by regulating intestinal microflora through the dampness-resolving method,which provides a theoretical reference for the research and clinical practice of traditional Chinese medicine intervention in IBS-D.关键词
化湿法/肠道菌群/泄泻/肠易激综合征Key words
Dampness-resolving method/Intestinal microflora/Diarrhea/Irritable bowel syndrome分类
医药卫生引用本文复制引用
陶瑞雪,张琪,刘凯,何美萍,张桢..基于"无湿不成泻"探讨化湿法调节肠道菌群治疗腹泻型肠易激综合征[J].中国医药科学,2024,14(7):30-34,5.基金项目
国家自然科学基金项目(82105032) （82105032）
重庆市自然科学基金面上项目(CSTB2022NSCQ-MSX0392) （CSTB2022NSCQ-MSX0392）
重庆市科卫联合中医药科研项目(2023QNXM052) （2023QNXM052）
重庆市科卫联合医学科研项目(2022QNXM075). （2022QNXM075）
