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组织工程骨移植物的血管化策略研究

张一帆 张郭 汪振星 孙家明

组织工程与重建外科杂志2024,Vol.20Issue(2):234-239,264,7.
组织工程与重建外科杂志2024,Vol.20Issue(2):234-239,264,7.DOI:10.3969/j.issn.1673-0364.2024.02.014

组织工程骨移植物的血管化策略研究

Research on vascularization strategy of bone tissue engineering graft

张一帆 1张郭 1汪振星 1孙家明1

作者信息

  • 1. 430022 湖北省武汉市 华中科技大学同济医学院附属协和医院整形外科
  • 折叠

摘要

Abstract

Bone tissue engineering is a promising method for repairing large-scale bone defects.Bone is a dynamic and highly vascularized tissue,and the formation of vascular tissue in an appropriate time is the key to ensure the survival,repair and remodeling of bone graft,as well as one of the main challenges of bone tissue engineering.In this paper,the research progress of vascularization of bone tissue engineering grafts from the perspective of the significance of vascularization and strategies based on seed cells,angiogenic factors,scaffold structure,immune regulation,and prevascularization was reviewed.

关键词

组织工程/大段骨缺损/移植物/血管化/骨修复

Key words

Tissue engineering/Large-scale bone defect/Graft/Vascularization/Bone regeneration

分类

医药卫生

引用本文复制引用

张一帆,张郭,汪振星,孙家明..组织工程骨移植物的血管化策略研究[J].组织工程与重建外科杂志,2024,20(2):234-239,264,7.

组织工程与重建外科杂志

OACSTPCD

1673-0364

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