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体外三维功能性皮肤组织模型构建研究进展

李洋 惠涛涛 张波 薛子阳 蔡茂 王琳

组织工程与重建外科杂志2024,Vol.20Issue(2):240-247,8.
组织工程与重建外科杂志2024,Vol.20Issue(2):240-247,8.DOI:10.3969/j.issn.1673-0364.2024.02.015

体外三维功能性皮肤组织模型构建研究进展

Research progress of three-dimensional functional skin model construction in vitro

李洋 1惠涛涛 1张波 1薛子阳 1蔡茂 1王琳1

作者信息

  • 1. 710077 陕西省西安市 西安外事学院医学院||710077 陕西省西安市 西安外事学院生命科学应用研究院||710077 陕西省西安市 精准抗衰健康产品研发与转化陕西省高校工程研究中心
  • 折叠

摘要

Abstract

Tissue engineering technology has been widely used in tissue and organ repair and has become an important method of regenerative medicine technique.The appearance of tissue engineering skin provides a new method for the treatment of large-area cutaneous defect in clinic.Because of the complicated skin-structure,it is an enormous challenge to building a functional three-dimensional skin tissue engineering model to simulate or replace the original skin.Based on this,from the aspects of cell types and sources,techniques,types,applications and prospects of skin tissue engineering models,the latest progress of in vitro 3D functional skin tissue model construction was reviewed in order to provide a theoretical basis for the construction of ideal skin tissue model.

关键词

三维/组织工程/皮肤模型/再生医学

Key words

Three-dimensional/Tissue engineering/Skin model/Regenerative medicine

分类

医药卫生

引用本文复制引用

李洋,惠涛涛,张波,薛子阳,蔡茂,王琳..体外三维功能性皮肤组织模型构建研究进展[J].组织工程与重建外科杂志,2024,20(2):240-247,8.

基金项目

国家自然科学基金青年科学基金项目(31900939) (31900939)

陕西省"千人计划"青年项目 ()

陕西省重点研发计划(2023-YBSF-039) (2023-YBSF-039)

陕西高校青年创新团队. ()

组织工程与重建外科杂志

OACSTPCD

1673-0364

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