组织工程与重建外科杂志2024，Vol.20Issue(2)：254-259,6.DOI:10.3969/j.issn.1673-0364.2024.02.017
先天性黑素细胞痣的发病机制及诊疗策略
The pathogenesis and therapeutic strategies for congenital melanocytic nevi
摘要
Abstract
Congenital melanocytic nevus is a common skin developmental abnormality that can occur in any part of the body where melanocytes are present.Its occurrence is closely related to somatic cell mutations,regulated by multiple signaling pathways,and has diverse clinical manifestations.Surgical excision and dilator are still the main treatments for CMN,and laser therapy is a powerful mean to eliminate pigmentation and remove satellite lesions.Targeted therapy and immunotherapy are becoming a new direction for the treatment of congenital melanin giant nevi.关键词
先天性黑素细胞痣/发病机制/体细胞突变/靶向治疗Key words
Congenital melanocytic nevus/Pathogenesis/Somatic mutation/Targeted therapy分类
医药卫生引用本文复制引用
李东东,王斌..先天性黑素细胞痣的发病机制及诊疗策略[J].组织工程与重建外科杂志,2024,20(2):254-259,6.基金项目
国家重点研发计划(2022YFC2703700,2022YFC2703704) （2022YFC2703700,2022YFC2703704）
上海市科学技术委员会临床医学研究中心项目(22MC1940300) （22MC1940300）
上海交通大学医学院附属第九人民医院先天性肢体畸形生物样本库建设项目(YBKB202108)、罕见病注册登记项目(JYHJB202205). （YBKB202108）
