组织工程与重建外科杂志2024，Vol.20Issue(2)：260-264,5.DOI:10.3969/j.issn.1673-0364.2024.02.018
隆突性皮肤纤维肉瘤的分子生物学进展
Advances in molecular genetics of dermatofibrosarcoma protuberans
摘要
Abstract
Dermatofibrosarcoma protuberans(DFSP),one of the most common skin sarcomas,lacks specific clinical and radiological features and exhibits complex histopathology.It is characterized by slow and irregular infiltration of surrounding tissues,and surgical resection is the primary treatment modality.Currently,DFSP presents clinical challenges in terms of high misdiagnosis and recurrence rates,necessitating the development of specific diagnostic markers and effective therapeutic targets.This article aimed to provide a comprehensive review of the latest molecular genetics advancements in DFSP,with the goal of offering new insights for its diagnosis and treatment.关键词
隆突性皮肤纤维肉瘤/分子生物学/重排/变异Key words
Dermatofibrosarcoma protuberans/Molecular biology/Rearrangement/Mutation分类
医药卫生引用本文复制引用
邓雨琦,梁筱,孙笛,刘菲,杨军..隆突性皮肤纤维肉瘤的分子生物学进展[J].组织工程与重建外科杂志,2024,20(2):260-264,5.基金项目
上海市科学技术委员会临床医学研究中心项目(22MC1940300). （22MC1940300）
