前庭阵发症的临床评估与进展OA北大核心CSTPCD
Advances in Clinical Evaluation of Vestibular Paroxysmia
前庭阵发症(vestibular paroxysmia,VP)是一种相对罕见的眩晕疾病,其病因机制尚待进一步研究.目前,VP症状为主要诊断依据,而影像学、前庭功能检查及听力学检查等辅助检查可作为排除依据.治疗手段主要以药物治疗为主,尤其是小剂量卡马西平或奥卡西平.对于药物可控的患者,手术非必需选择.阵发性耳鸣和打字机耳鸣可能是血管压迫耳蜗神经的特异性指标,但仍需要进一步研究验证.未来研究的方向应包括针对VP的确诊及治疗手段,以期精准医学在此类疾病的诊疗中发挥更大作用.我们主要对VP的发病机制、诊断标准、临床表现以及治疗方法进行综述.
Vestibular Paroxysmia(VP)is a rare vertigo disorder,whose etiological mechanism remains to be fur-ther studied.At present,symptoms are the main basis for diagnosis,and imaging,vestibular function examination and audiology examination and other auxiliary tests can be used to exclude other disorders.The main treatment methods are drug therapy,especially low-dose carbamazepine(CBZ)or oxamazepine(OXC).Surgery is not necessarily indicated in patients manageable with medications.Paroxysmal tinnitus and typewriter tinnitus may be specific indicators of vascu-lar compression of the cochlear nerve,but additional studies are needed to confirm the diagnosis.The direction of future research should focus on the diagnosis and treatment of VP,to facilitate precision medicine in this disease.This article mainly reviews the pathogenesis,diagnostic criteria,clinical manifestations and treatment of VP.
胡全福;杜一;徐正燕;廖镇密;王郁;刘兴健;吴子明
重庆市梁平区人民医院耳鼻咽喉科(重庆 405200)||中国人民解放军总医院耳鼻咽喉头颈外科医学部,听觉与平衡觉全国重点实验室,国家耳鼻咽喉疾病临床医学研究中心,聋病教育部重点实验室,聋病防治北京市重点实验室中国人民解放军总医院耳鼻咽喉头颈外科医学部,听觉与平衡觉全国重点实验室,国家耳鼻咽喉疾病临床医学研究中心,聋病教育部重点实验室,聋病防治北京市重点实验室重庆市梁平区人民医院耳鼻咽喉科(重庆 405200)
前庭阵发症发病机制诊断标准临床表现治疗方法综述
vestibular paroxysmiapathogenesisdiagnostic criteriaclinical manifestationstreatmentreview
《中华耳科学杂志》 2024 (001)
9-13 / 5
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