中国康复理论与实践2024，Vol.30Issue(4)：462-467,6.DOI:10.3969/j.issn.1006-9771.2024.04.012
多通道功能性电刺激结合任务导向训练对脑卒中上肢偏瘫患者脑功能网络的即刻影响
Immediate effect of multi-chancel functional electrical stimulation combined with task-oriented training on brain functional network in stroke patients with upper limb hemiplegia
摘要
Abstract
Objective To observe the change of brain functional network of stroke patients with upper limb hemiplegia during task-oriented training under multi-channel functional electrical stimulation(FES)using functional near-infrared spec-troscopy(fNIRS). Methods From April to October,2023,15 stroke inpatients with upper limb hemiplegia were selected from the First Peo-ple's Hospital of Yancheng.They accepted task-oriented training,under real stimulation and sham stimulation de-termined with tossing a coin,with an interval of a day.The real stimulation was induced with multi-channel FES,and sham stimulation was induced with no stimulation.During the training,fNIRS was used to measure the con-centrations of oxygenated hemoglobin in the bilateral prefrontal cortex(PFC),premotor cortex(PMC),supple-mentary motor area(SMA)and sensorimotor cortex(SMC),to obtain the overall functional connectivity and the difference of functional connectivity based on region of interest. Results Compared with the sham stimulation,the overall functional connectivity reduced(t =-2.735,P<0.05);the functional connectivity between the contralesional PFC to ipsilateral PFC,and the contralesional PFC to contrale-sional PMC also reduced(P<0.05)under real stimulation. Conclusion Multi-channel FES combined with task-oriented training can optimize the cortical functional connectivity in stroke patients with upper limb hemiplegia.关键词
脑卒中/多通道功能性电刺激/任务导向训练/功能性近红外光谱/脑功能网络Key words
stroke/multi-channel functional electrical stimulation/task-oriented training/functional near-infrared spectroscopy/brain functional network分类
医药卫生引用本文复制引用
陈园月,李加斌,蒯凤,彭丽丽,项洁..多通道功能性电刺激结合任务导向训练对脑卒中上肢偏瘫患者脑功能网络的即刻影响[J].中国康复理论与实践,2024,30(4):462-467,6.基金项目
国家重点研发计划项目(No.2020YFC2006604) Supported by National Key Research and Development Program of China(No.2020YFC2006604) （No.2020YFC2006604）
