中国康复理论与实践2024，Vol.30Issue(4)：487-492,6.DOI:10.3969/j.issn.1006-9771.2024.04.015
创伤性颈脊髓损伤患者华勒氏变性的磁共振成像研究
Wallerian degeneration in patients with traumatic cervical spinal cord injury:a magnetic resonance imaging study
摘要
Abstract
Objective To explore the signal characteristics of Wallerian degeneration(WD)of the spinal cord in patients with trau-matic cervical spinal cord injury. Methods A retrospective analysis was conducted.From January,2015 to December,2021,the clinical data of 191 pa-tients with traumatic cervical spinal cord injury in Beijing Boai Hospital were included.According to sagittal and axial T2-weighted images(T2WI)of routine cervical magnetic resonance imaging(MRI),the patients were divid-ed into WD group and non-WD group.The gender,age,mechanism of injury,American Spinal Injury Associa-tion Impairment Scale(AIS),neurological level,and time interval to obtain MRI after injury were compared be-tween two groups.The characteristics of WD in dorsal column(DC),lateral spinothalamic tract(ST)and lateral corticospinal tract(CS)were analyzed. Results A total of 115 cases(60.2%)showed WD.There were significant differences in age,mechanism of injury,AIS grade,and time interval to obtain MRI after injury between two groups(Z>3.820,χ2>9.104,P<0.05).In WD group,the occurrence rates of WD in DC and ST above the injury site were 100%and 87%,respectively.Below the injury site,the occurrence rate of WD in CS was 35.7%.Based on the pattern of WD signal appearance,three groups were identified:15 cases(13%)had only DC signal changes,59 cases(51.3%)had changes in both DC and ST,and 41 cases(35.7%)had changes in all the three locations(DC,ST and CS).There was significant dif-ference in the time interval to obtain MRI after injury(H = 90.794,P<0.05)among three groups,while there was no significance in AIS grade(P>0.05). Conclusion Routine MRI examination with T2WI could detect WD signals in patients with traumatic cervical spinal cord injury,and the occurrence of WD is associated with post-injury time.关键词
创伤性颈脊髓损伤/华勒氏变性/磁共振成像/美国脊柱损伤协会残损分级Key words
traumatic cervical spinal cord injury/Wallerian degeneration/magnetic resonance imaging/American Spinal Injury Association Impairment Scale分类
医药卫生引用本文复制引用
袁媛,康海琼,逯晓蕾,蒙倩茹,周红俊,卫波,丛欣莹,刘根林,郑樱,郝春霞,张缨,王一吉..创伤性颈脊髓损伤患者华勒氏变性的磁共振成像研究[J].中国康复理论与实践,2024,30(4):487-492,6.基金项目
国家重点研发计划项目(No.2020YFC2007505) Supported by China National Key R&D Program(No.2020YFC2007505) （No.2020YFC2007505）
