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基于纳米电极的单细胞内生物分子电化学分析

刘康 潘荣容 江德臣

高等学校化学学报2024,Vol.45Issue(5):1-9,9.
高等学校化学学报2024,Vol.45Issue(5):1-9,9.DOI:10.7503/cjcu20240027

基于纳米电极的单细胞内生物分子电化学分析

Electrochemical Analysis of Intracellular Molecules at Single Cells Based on Nanoelectrodes

刘康 1潘荣容 1江德臣1

作者信息

  • 1. 南京大学化学化工学院,生命分析化学国家重点实验室,南京 210092
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摘要

Abstract

Single-cell analysis enables more accurate acquisition of biological information and avoids the loss of single-cell heterogeneity features from averaging analysis,which is essential for studies to elucidate cell metabolism and signaling pathways.Electrochemical analysis techniques based on nanoelectrodes are widely used in single-cell analysis because of their high selectivity,high sensitivity and high spatiotemporal resolution.In this review,the latest research progress of the quantitative analysis of intracellular biomolecules in single cells using nanoelectrodes is reviewed.Moreover,its application in biological research and the challenges are introduced.

关键词

单细胞/单细胞器/生物分子/电化学分析/纳米电极

Key words

Single cell/Single organelle/Biomolecule/Electrochemistry/Nanoelectrode

分类

化学化工

引用本文复制引用

刘康,潘荣容,江德臣..基于纳米电极的单细胞内生物分子电化学分析[J].高等学校化学学报,2024,45(5):1-9,9.

基金项目

国家杰出青年科学基金(批准号:22025403)资助. Supported by the National Science Fund for Distinguished Young Scholars,China(No.22025403). (批准号:22025403)

高等学校化学学报

OA北大核心CSTPCD

0251-0790

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