摘要
Abstract
Objective To analyze the effect of standard large trauma craniotomy combined with mild-hypothermia in se-vere craniocerebral trauma.Methods 76 cases of patients with severe craniocerebral trauma were selected,and they all were divided into an experimental group(n=38)and a control group(n=38)according to the method of random number table.The control group was treated with standard large trauma craniotomy,while the experimental group was treated with standard large trauma craniotomy combined with mild-hypothermia.The clinical efficacy,intracranial pressure level,national institute of health stroke scale(NIHSS)score,immune function(CD8+、CD4+)level and complicationsoccurrence rate of the two groups were com-pared.Results The total effective rate 94.74%(36/38)of the experimental groupwas higher than73.68%(28/38)of the control group(P＜0.05);After 1d,2d and 3d of treatment,the levels of intracranial pressure in the experimental group was lower than that in the control group(P＜0.05);After treatment,the NIHSS score of the experimental group was lower than that of the control group(P＜0.05);After treatment,the level of CD8+ in the experimental group was lower than that in the control group,while the level of CD4+ was higher than that in the control group(P＜0.05);The occurrence rate of complications 5.26%(2/38)in the experimental group waslower than 26.32%(10/38)in the control group(P＜0.05).Conclusion The standard large trau-macraniotomy combined with mild-hypothermia in the treatment of severe craniocerebral trauma can improve the clinical effi-cacy,decrease the level of intracranial pressure,improve the state of neurological injury,improve the immune function and re-duce the occurrence ofpostoperative complications.关键词
重型颅脑外伤/亚低温/免疫功能/标准外伤大骨瓣开颅术Key words
Severe craniocerebral trauma/Sub-low temperature/Immunityfunction/Standard large trauma craniotomy分类
医药卫生
