化工进展2024，Vol.43Issue(4)：2001-2016,16.DOI:10.16085/j.issn.1000-6613.2023-0626
伪蛋白生物材料的分类、合成及其应用
Pseudo-protein biomaterials:Classification,synthesis and application
摘要
Abstract
Pseudo-protein is a new synthetic biodegradable material.It takes amino acids as the basic structural unit.Unlike protein,pseudo-protein has other linking groups in addition to peptide bonds,which gives it not only the excellent properties of proteins,but also the good mechanical properties,thermal properties,adjustable physicochemical properties,excellent cytocompatibility,3D microporous structure,etc.Therefore,pseudo-proteins can be effectively applied in carriers,wound healing,tissue engineering,etc.Firstly,this paper reviews the types of pseudo-proteins studied so far,including non-functional and functional pseudo-proteins,followed by a detailed description of the methods for the synthesis of pseudo-proteins by condensation,including solution polycondensation,interfacial polymerization,melt polycondensation and ring-opening polymerization,and then summarizes the applications of pseudo-protein biomaterials in drug carrier,gene carrier,tissue engineering and wound dressing.Finally,the future development of synthetic routes and applications of pseudo-protein biomaterials is prospected.关键词
伪蛋白/合成/聚合物/载体/组织工程Key words
pseudo-protein/synthesis/polymers/carrier/tissue engineering分类
化学化工引用本文复制引用
薛云娇,张璇,刘洋,陈玉焕,房静,杨芳..伪蛋白生物材料的分类、合成及其应用[J].化工进展,2024,43(4):2001-2016,16.基金项目
2022年度引进留学人员资助项目(重点)(C20220502). （重点）
