原发性梗阻性巨输尿管症患儿术后尿路感染的危险因素分析OA北大核心CSTPCD

Objective To explore the risk factors for postoperative urinary tract infections(UTIs)in children of primary obstructive megaureter(POM).Methods From January 2015 to February 2023,retro-spective analysis was performed for the relevant clinical data of 146 POM children.There were 97 boys and 49 girls with a median age of 23(1-17)month.The involved side was left(n=89),right(n=40)and bilateral(n=17).According to the results of postoperative urinary culture,they were assigned into two groups of infec-ted(n=35)and non-infected(n=111).Operative duration,surgical approach,severity of hydronephrosis,u-reteral width,preoperative hematological parameters,leucocyte count of preoperative urine routine,postoperative urinary routine/culture,double J tubing or not,urinary catheterization and bladder fistulas were recorded.Statis-tical analysis was performed for risk factors for postoperative UTIs.Results The results of univariate Logistic regression analysis indicated that age ≤1 year,leucocyte count of preoperative urine routine＞5/HPF and se-verity of hydronephrosis＞3 were risk factors for postoperative UTIs(P＜0.05).The results of multivariate Lo-gistic regression analysis revealed that the risk of postoperative UTIs in children aged≤1 year was 3.462 folds higher than that in those aged＞1 year(OR=3.462,95％CI:1.245-9.629,P=0.017).The risk of postop-erative UTIs in children with leucocyte count of preoperative urine routine＞5/HPF was 5.451 folds higher than that those with leucocyte count of preoperative urine routine≤5/HPF(OR=5.451,95％CI:2.227-13.045,P＜0.001).The risk of postoperative UTIs in children with hydronephrosis＞grade Ⅲ was 5.473 folds higher than that in those with hydronephrosis ≤ grade Ⅲ(OR=5.473,95％CI:1.135-26.390,P=0.034).Conclusions Young POM children with leucocyte count of preoperative urine routine＞5/HPF are more prone to postoperative UTIs.