临床小儿外科杂志2024，Vol.23Issue(4)：341-347,7.DOI:10.3760/cma.j.cn101785-202304036-008
原发性梗阻性巨输尿管症患儿术后尿路感染的危险因素分析
Risk factors for postoperative urinary tract infections in children with primary obstructive megaureter
摘要
Abstract
Objective To explore the risk factors for postoperative urinary tract infections(UTIs)in children of primary obstructive megaureter(POM).Methods From January 2015 to February 2023,retro-spective analysis was performed for the relevant clinical data of 146 POM children.There were 97 boys and 49 girls with a median age of 23(1-17)month.The involved side was left(n=89),right(n=40)and bilateral(n=17).According to the results of postoperative urinary culture,they were assigned into two groups of infec-ted(n=35)and non-infected(n=111).Operative duration,surgical approach,severity of hydronephrosis,u-reteral width,preoperative hematological parameters,leucocyte count of preoperative urine routine,postoperative urinary routine/culture,double J tubing or not,urinary catheterization and bladder fistulas were recorded.Statis-tical analysis was performed for risk factors for postoperative UTIs.Results The results of univariate Logistic regression analysis indicated that age ≤1 year,leucocyte count of preoperative urine routine＞5/HPF and se-verity of hydronephrosis＞3 were risk factors for postoperative UTIs(P＜0.05).The results of multivariate Lo-gistic regression analysis revealed that the risk of postoperative UTIs in children aged≤1 year was 3.462 folds higher than that in those aged＞1 year(OR=3.462,95％CI:1.245-9.629,P=0.017).The risk of postop-erative UTIs in children with leucocyte count of preoperative urine routine＞5/HPF was 5.451 folds higher than that those with leucocyte count of preoperative urine routine≤5/HPF(OR=5.451,95％CI:2.227-13.045,P＜0.001).The risk of postoperative UTIs in children with hydronephrosis＞grade Ⅲ was 5.473 folds higher than that in those with hydronephrosis ≤ grade Ⅲ(OR=5.473,95％CI:1.135-26.390,P=0.034).Conclusions Young POM children with leucocyte count of preoperative urine routine＞5/HPF are more prone to postoperative UTIs.关键词
原发性梗阻性巨输尿管/输尿管梗阻/泌尿系感染/危险因素/儿童Key words
Primary Obstructive Megaureter/Ureteral Obstruction/Urinary Tract Infections/Risk Factors/Child引用本文复制引用
房文娟,陈鹏宇,刘晓东,李守林..原发性梗阻性巨输尿管症患儿术后尿路感染的危险因素分析[J].临床小儿外科杂志,2024,23(4):341-347,7.基金项目
国家自然科学基金委联合基金项目(U1904208) （U1904208）
深圳市医学重点学科(2020-2024)(SZXK035) Natural Science Foundation of China(U1904208) （2020-2024）
Shenzhen Municipal Fund for Guang-dong Provincial High-level Key Clinical Specialties(2022-2024)(SZXK035) （2022-2024）
