日用化学工业（中英文）2024，Vol.54Issue(5)：514-519,6.DOI:10.3969/j.issn.2097-2806.2024.05.003
哌嗪型双核酸性离子液体催化合成苯甲酸甲酯
Study on the synthesis of methyl benzoate from benzoic acid catalyzed by dual-core piperazine-based ionic liquids
摘要
Abstract
Benzoates are important intermediates for preparing perfume essence and artificial essential oils.For conventional esterification of benzoic acid with methanol,protonic acids such as HCl,H2SO4,have been used,which is harmful to equipment and shows low product yield.Using ionic liquids as solvents or catalysts can make the reaction conditions stable,recyclable,and environment-friendly,and lead to high product yield.In this work,a series of sulfonic-acid-functionalized dual-core piperazine-based ionic liquids,such as 1,4-bis[N-methyl-N-(3-sulfopropyl)]piperazine bis(p-toluenesulfonate)([BMSP][PSA]),1,4-bis[N-methyl-N-(3-sulfopropyl)]piperazine dimethanesulfonate([BMSP][MSA]),and 1,4-bis[N-methyl-N-(3-sulfopropyl)]piperazine bis(hydrosulfate)([BMSP][SA]),were synthesized by a two-step process.The molecular structure of[BMSP][PSA]was characterized by FT-IR,1H NMR and TGA-DTG.It exhibited good thermal stability.The results showed that the three sulfonic-acid-functionalized dual-core piperazine-based ionic liquids had excellent catalytic activity,among which the synthesized[BMSP][PSA]exhibited the best catalytic activity.The conversion of benzoic acid reached 97.6%under the conditions of alcohol-acid ratio of 16∶1,reaction temperature of 70℃,reaction time of 3 h,and catalyst dosage of 3 mmol.The conversion for esterification still reached 93.9%after 4 cycles with the catalyst,which showed excellent catalytic activity.Therefore,it was a good candidate of green catalyst for industrial production.关键词
离子液体/酯化反应/苯甲酸甲酯/1,4-二甲基哌嗪Key words
ionic liquid/esterification/methyl benzoate/1,4-dimethylpiperazine分类
化学化工引用本文复制引用
李祥,尹慧,旷宇阳,刘宁..哌嗪型双核酸性离子液体催化合成苯甲酸甲酯[J].日用化学工业（中英文）,2024,54(5):514-519,6.基金项目
湖南省教育厅科学研究项目重点项目(22A0628) （22A0628）
湖南省自然科学基金青年项目(2020JJ5117) （2020JJ5117）
湖南省大学生创新创业训练计划项目(S202311528069,S202211528057) （S202311528069,S202211528057）
