药学研究2024，Vol.43Issue(4)：373-379,7.DOI:10.13506/j.cnki.jpr.2024.04.011
HDL向肝转运的生物学基础及作为药物载体应用的研究进展
Research progress on the biological basis of HDL transport to liver and its application as drug carrier
摘要
Abstract
The development of biomimetic nanoparticle drug delivery systems is an emerging field with enormous poten-tial for efficient drug delivery.High density lipoprotein(HDL),as a natural nanocarrier,possesses features such as high transport efficiency,high safety,specific targeting,and strong penetrabillity,making it a potential drug carrier.The research on HDL-based nanoparticle drug delivery systems is increasingly gaining attention.This article reviewed the biological basis of HDL,including its composition,structure,metabolism,and its current status of research and application as a drug carrier of reconstituted HDL.The aim of this article is to provide new ideas for the in-depth study of HDL as drug carrier materials.关键词
高密度脂蛋白/逆向转运/清道夫受体/药物递送系统/纳米药物Key words
High-density lipoprotein/Reverse transport/Scavenger receptor/Drug delivery system/Nanomedicine分类
医药卫生引用本文复制引用
金许曈,江子贤,王馨怡,田吉来..HDL向肝转运的生物学基础及作为药物载体应用的研究进展[J].药学研究,2024,43(4):373-379,7.基金项目
南京中医药大学大学生创新创业训练计划项目(No.103152022028) （No.103152022028）
