陕西医学杂志2024,Vol.53Issue(5):703-706,4.DOI:10.3969/j.issn.1000-7377.2024.05.029
三氧化二砷在肿瘤治疗中临床应用及相关分子机制研究进展
Research progress on clinical application and related molecular mechanism of arsenic trioxide in tumor treatment
摘要
Abstract
Arsenic trioxide(ATO)has a wide range of anti-tumor effects and has been used to treat diseases for more than 2000 years.ATO has been used in the treatment of acute promyelocytic leukemia(APL)since the 1970s.Increasing evidence has shown that ATO also exerts anti-tumor effects in other cancers,such as multiple mye-loma,liver cancer and pancreatic cancer.This article reviews the clinical application and related molecular mechanisms of ATO in tumor treatment.关键词
三氧化二砷/肿瘤/急性早幼粒细胞白血病/临床应用/分子机制Key words
Arsenic trioxide/Tumors/Acute promyelocytic leukemia/Clinical application/Molecular mechanisms分类
医药卫生引用本文复制引用
李欣,潘宇飞,万旭英..三氧化二砷在肿瘤治疗中临床应用及相关分子机制研究进展[J].陕西医学杂志,2024,53(5):703-706,4.基金项目
国家自然科学基金资助面上项目(82373223) (82373223)
上海市卫生健康委员会科研项目(202340091) (202340091)