实验科学与技术2024，Vol.22Issue(2)：76-80,5.DOI:10.12179/1672-4550.20220452
绿色肟化反应的综合实验设计
Design on the Comprehensive Experiment for the Green Oximation Reaction
摘要
Abstract
According to some research achievements,a green oximation comprehensive experiment was designed to overcome the shortcomings of the traditional oximation reaction,and the base and reaction equipment were improved.Recyclable nano-K2CO3 was prepared firstly by ultrafine wet milling and characterized by the laser particle size analyzer,scanning electronic microscopy(SEM),and CO2-TPD.The synthesis of ethyl α-(hydroxyimino)benzenepropanoate was performed using nano-K2CO3 as the base.The preparation of ethyl nitrite and oximation of diethyl benzylmalonate were carried out simultaneously by series devices.The experiment avoids the shortcomings of sodium alkoxides that cannot be recovered and corrodes equipment,and solves the problems of storage and transportation difficulties and easy environmental pollution of volatile nitrite.This comprehensive experiment is beneficial for students to learn the idea of environment-friendly green chemistry,improve the students'comprehensive ability and quality,and cultivate their scientific research innovation thinking ability.关键词
纳米颗粒/绿色化学/肟化反应/碳酸钾/综合实验Key words
nanoparticles/green chemistry/oximation reaction/potassium carbonate/comprehensive experiment分类
医药卫生引用本文复制引用
范士明,余伟,李傲齐,董思凡,韩天佼..绿色肟化反应的综合实验设计[J].实验科学与技术,2024,22(2):76-80,5.基金项目
国家自然科学基金(21978068) （21978068）
河北省自然科学基金(H2020208030) （H2020208030）
河北科技大学研究生课程思政项目(1200769). （1200769）
