实用医学杂志2024，Vol.40Issue(9)：1181-1185,5.DOI:10.3969/j.issn.1006-5725.2024.09.001
慢性阻塞性肺疾病合并肌少症的研究进展
Sarcopenia associated with chronic obstructive pulmonary disease
摘要
Abstract
Sarcopenia is a progressive and systemic skeletal muscle disease and an important extrapulmo-nary complication of chronic obstructive pulmonary disease(COPD).Multiple studies have confirmed that COPD patients with sarcopenia have more severe airflow obstruction and emphysema,higher dyspnea index scores,reduced quality of life and exercise capacity,frequent acute exacerbations,and increased mortality.Although sarcopenia has been mentioned as a complication of COPD for many years,current clinical practice has received insufficient attention and insufficient intervention.The main reason is that its pathogenesis is unknown and drug treatment regi-mens are ineffective.As more and more research has been done on COPD combined with sarcopenia in recent years,this article reviews the current research progress to pay attention to further research and early intervention,including new mechanisms,diagnostic criteria,and drug treatment progress.关键词
慢性阻塞性肺疾病/肌少症/进展Key words
chronic obstructive pulmonary disease/sarcopenia/progress分类
医药卫生引用本文复制引用
杨士芳,高兴林,李静,姬路鹏..慢性阻塞性肺疾病合并肌少症的研究进展[J].实用医学杂志,2024,40(9):1181-1185,5.基金项目
中华国际医学交流基金会呼吸疾病青年实用研究项目(编号:Z2017242301) （编号:Z2017242301）
