实用医学杂志2024，Vol.40Issue(9)：1268-1274,7.DOI:10.3969/j.issn.1006-5725.2024.09.015
单纯手术与手术联合糖皮质激素治疗肿块型肉芽肿性乳腺炎的临床疗效
Clinical efficacy of simple surgery and surgery combined with glucocorticoids in the treatment of mass type granulomatous mastitis
摘要
Abstract
Objective To compare and analyze the clinical efficacy,recurrence rate,and breast appear-ance evaluation of simple surgery and surgery combined with glucocorticoids in the treatment of mass type granuloma-tous mastitis.Methods This study retrospectively analyzed 106 patients with nodular granulomatous mastitis who visited the Department of Breast Surgery at Yichang Central People's Hospital from January 2017 to January 2022 as the study subjects.According to the different treatment methods during the visit,patients were divided into Group A with simple surgical treatment(n = 67)and Group B with surgery combined with glucocorticoid treatment(n = 39).The general information and clinical indicators of the two groups of patients were observed and compared.Obtain patient clinical efficacy,time to clinical cure(TTCR),recurrence rate within one year,and breast appearance evaluation through follow-up.Results The prognosis of the follow-up patients after treatment showed that Group B patients had better clinical cure rate and one-year recurrence rate than the simple surgery group(P＜0.05).More-over,the difference in breast appearance evaluation between the two groups was statistically significant,with Group B patients having a significantly higher rate of excellent appearance(88.06%)than Group A(92.31%).According to statistics,only 5.13%of patients in Group B experienced gastrointestinal reactions within one year after taking hormone therapy.Conclusions The combination of surgery and glucocorticoids in the treatment of mass type GM can effectively improve the overall clinical treatment effect of patients,reduce the short-term recurrence rate,and have a significant effect on ensuring the integrity of breast appearance.At the same time,low-dose oral steroid drugs have fewer adverse reactions and high safety.关键词
肉芽肿性乳腺炎/糖皮质激素/手术治疗/临床治愈率/复发率Key words
granulomatous mastitis/glucocorticoids/surgical treatment/clinical cure rate/recur-rence rate分类
医药卫生引用本文复制引用
崔天玥,欧阳理权,张胜初..单纯手术与手术联合糖皮质激素治疗肿块型肉芽肿性乳腺炎的临床疗效[J].实用医学杂志,2024,40(9):1268-1274,7.基金项目
湖北省教育厅科学技术研究计划优秀中青年人才项目(编号:Z2021230) （编号:Z2021230）
