实用医学杂志2024，Vol.40Issue(9)：1320-1323,4.DOI:10.3969/j.issn.1006-5725.2024.09.024
microRNAs对心脏电生理特性影响的研究进展
Research progress in the effects of microRNAs on cardiac electrophysiological properties
摘要
Abstract
The incidence of perioperative arrhythmias is 4%～20%in noncardiac surgery and 10%～30%in cardiothoracic surgery,with the incidence of perioperative arrhythmias in cardiac surgery patients as high as 90%.Perioperative arrhythmias can prolong hospitalization and increase morbidity and mortality during hospitalization.Studies have shown that aberrantly expressed microRNAs in cardiovascular diseases can participate in cardiac auto-maticity,excitability and conductivity by regulating ion channels,gap junction proteins,and intracellular Ca2+ handling proteins,thereby regulating cardiac electrophysiological homeostasis and arrhythmias.In this article,we will review the research progress of microRNAs and arrhythmias mainly from the perspective of cardiac electrophysi-ological imbalance.关键词
microRNA/心脏电生理/心律失常Key words
microRNA/cardiac electrophysiology/arrhythmia分类
医药卫生引用本文复制引用
易菁,高鸿,潘斯斯..microRNAs对心脏电生理特性影响的研究进展[J].实用医学杂志,2024,40(9):1320-1323,4.基金项目
国家自然科学基金项目(编号:82360053) （编号:82360053）
贵州省卫生健康委科学技术基金项目(编号:Gzwkj2021-270,Gzwkj2022-131) （编号:Gzwkj2021-270,Gzwkj2022-131）
贵州省中医药、民族医药科学技术研究专项课题项目(编号:QZYY-2021-102) （编号:QZYY-2021-102）
