云南化工2024，Vol.51Issue(4)：44-53,10.DOI:10.3969/j.issn.1004-275X.2024.04.10
CO-CO2体系合成氘代甲醇热力学分析及正交优化
Thermodynamic Analysis and Orthogonal Optimization of Synthesis of Deuterated Methanol Catalyst in CO-CO2 System
摘要
Abstract
As an important chemical raw material and deuterated intermediate,deuterated methanol(CD3OD)has been widely used in nuclear magnetic resonance reagents,deuterated drug intermediates and photoelectric materials modification,but its catalytic synthesis efficiency in CO-CO2 system still needs to be improved.Herein,the effect of reaction conditions on the equilibrium conversion rate during the process of prepara-tion of deuterated methanol from CO-CO2 and D2 is calculatedally.In the case of CuO/ZnO/Al2O3 catalyst,the optimal reaction conditions for the synthesis of deuterated methanol is investigated by orthogonal experiment.Taking the space-time yield of deuterated methanol as the index,the optimal reaction conditions obtained in the experiment are as follows:the reaction temperature is 240 ℃,the reaction pressure is 5 MPa;the molar ratio of D2/(CO+CO2)is 3,and the molar ratio of CO/CO2 is 1.关键词
氘代甲醇/热力学/合成条件优化Key words
Deuterated Methanol/Thermodynamic/Optimization of Synthetic Conditions分类
化学化工引用本文复制引用
龙涛,周锋,张伟,吴泓,王建,陈霖..CO-CO2体系合成氘代甲醇热力学分析及正交优化[J].云南化工,2024,51(4):44-53,10.基金项目
国家重点基础研究发展计划(2018YFC1901604) （2018YFC1901604）
湖南省自然科学基金(2023JJ30667) （2023JJ30667）
中南大学研究生教育教学改革项目(2021JGB117). （2021JGB117）
