CO-CO2体系合成氘代甲醇热力学分析及正交优化OA

As an important chemical raw material and deuterated intermediate,deuterated methanol(CD3OD)has been widely used in nuclear magnetic resonance reagents,deuterated drug intermediates and photoelectric materials modification,but its catalytic synthesis efficiency in CO-CO2 system still needs to be improved.Herein,the effect of reaction conditions on the equilibrium conversion rate during the process of prepara-tion of deuterated methanol from CO-CO2 and D2 is calculatedally.In the case of CuO/ZnO/Al2O3 catalyst,the optimal reaction conditions for the synthesis of deuterated methanol is investigated by orthogonal experiment.Taking the space-time yield of deuterated methanol as the index,the optimal reaction conditions obtained in the experiment are as follows:the reaction temperature is 240 ℃,the reaction pressure is 5 MPa;the molar ratio of D2/(CO+CO2)is 3,and the molar ratio of CO/CO2 is 1.