云南化工2024，Vol.51Issue(4)：104-110,7.DOI:10.3969/j.issn.1004-275X.2024.04.25
基于UPLC-MS/MS法测定化妆品中31种抗感染类药物含量的不确定度评定
Uncertainty Evaluation for Determination of 31 Anti-infection Drugs in Cosmetics by UPLC-MS/MS
胡祖艳 1张伟 1苏锦华 1刀建华 1张瑛 1周林1
作者信息
- 1. 西双版纳傣族自治州药品监督检验研究院,云南 景洪 666100
- 折叠
摘要
Abstract
(Objective)The uncertainty of content detection of 31 anti-infection drugs in cosmetics was analyzed and related factors affecting the quantitative detection of cosmetics were analyzed.(Methods)According to the determination of anti-infective drug in cosmetics in Safety and Technical Standards for Cosmetics(2015 Edition),according to JJF 1059.1-2012 Evaluation and Expression of Uncertainty in Measurement and JJF 1135-2005 Evaluation of Uncertainty in Chemical Analysis Measurement,a mathematical model for the determination of 31 anti-infec-tion drugs was established,and the source of uncertainty was analyzed and evaluated.(Results)The measurement uncertainty of this method mainly came from the standard substance and the preparation process of a series of standard working solutions.(Conclusion)The evaluation re-sults can provide a theoretical reference for the determination of anti-infective drugs in Cosmetics.关键词
不确定度/计量学/抗感染药物/化妆品/UPLC-MS/MSKey words
Uncertainty/Metrology/Anti-infection Drugs/Cosmetics/UPLC-MS/MS分类
通用工业技术引用本文复制引用
胡祖艳,张伟,苏锦华,刀建华,张瑛,周林..基于UPLC-MS/MS法测定化妆品中31种抗感染类药物含量的不确定度评定[J].云南化工,2024,51(4):104-110,7.
