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单细胞转录组测序技术在伤口愈合中的研究进展

王嘉厅 李冬青 吴信峰

中国美容医学2024,Vol.33Issue(5):175-179,5.
中国美容医学2024,Vol.33Issue(5):175-179,5.

单细胞转录组测序技术在伤口愈合中的研究进展

Advances in Single-cell Transcriptome Sequencing Technology in Wound Healing

王嘉厅 1李冬青 2吴信峰1

作者信息

  • 1. 北京协和医学院中国医学科学院皮肤病医院 江苏 南京 210042
  • 2. 北京协和医学院中国医学科学院皮肤病医院 江苏 南京 210042||北京协和医学院中国医学科学院皮肤病研究所 江苏省皮肤病与性病分子生物学重点实验室 江苏 南京 210042
  • 折叠

摘要

Abstract

Wound healing is a complex biological process of repairing the skin barrier after a skin injury or infection.Poor wound healing leads to dysfunction of the organism,which seriously affects the quality of life of patients and significantly increases their economic burden.With the development and maturation of high-throughput sequencing technology,single-cell transcriptome sequencing technology has been widely used in biomedical fields due to its unique advantages such as its ability to finely delineate cell subpopulations,assess cellular heterogeneity,track cell lineage,and identify rare cells.In this paper,we summarize the research progress of single-cell transcriptome sequencing technology in wound healing,aiming to provide a reference for basic and clinical research on wound healing.

关键词

单细胞转录组测序/伤口愈合/急性伤口/慢性伤口/病理性瘢痕

Key words

single-cell transcriptome sequencing/wound healing/acute wounds/chronic wounds/pathological scarring

分类

医药卫生

引用本文复制引用

王嘉厅,李冬青,吴信峰..单细胞转录组测序技术在伤口愈合中的研究进展[J].中国美容医学,2024,33(5):175-179,5.

基金项目

国家自然科学基金(编号:82272294) (编号:82272294)

中国美容医学

OACSTPCD

1008-6455

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